{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T22:32:57Z","timestamp":1792276377977,"version":"4.4.0"},"reference-count":4,"publisher":"Walter de Gruyter GmbH","issue":"3-4","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_iss-2020-0022_abs_001_w2aab3b7c25b1b6b1aab1c17b1Aa\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Extraskeletal Ewing\u2019s sarcoma is a rarity, with a renal primary in an adult, being even rarer. There is no consensus on the optimal imaging modality, as well as best therapeutic option, making them an enigma for clinicians.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_iss-2020-0022_abs_002_w2aab3b7c25b1b6b1aab1c17b2Aa\">\n                  <jats:title>Case presentation<\/jats:title>\n                  <jats:p>We report the case of a 34-year-old lady, a known case of invasive lobular carcinoma of the left breast (ER,PR positive, Her2neu negative), having completed treatment in 2017, wherein, on an ultrasound evaluation for left flank pain, was incidentally found to have a left renal mass. A CT scan corroborated with the ultrasound, with an additional Level 1, left renal vein thrombus. She underwent an open left radical nephrectomy with renal vein thrombectomy. Histopathology of the resected tumor revealed features of Ewing\u2019s sarcoma of the kidney, confirmed by Fluorescent In Situ Hybridisation (FISH) and Immunohistochemistry (IHC).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_iss-2020-0022_abs_003_w2aab3b7c25b1b6b1aab1c17b3Aa\">\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Primary renal Ewing\u2019s sarcoma in an adult is a rare occurrence, with no characteristic imaging features, and no universally accepted guideline based management protocols. Akin with standard Ewings sarcoma treatment strategies, a margin negative- radical nephrectomy with adjuvant chemotherapy, seems the most apt treatment strategy.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/iss-2020-0022","type":"journal-article","created":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T05:29:12Z","timestamp":1611379752000},"page":"111-113","source":"Crossref","is-referenced-by-count":5,"title":["Primary renal Ewing\u2019s sarcoma in an adult: an enigma"],"prefix":"10.1515","volume":"5","author":[{"given":"Suvraraj","family":"Das","sequence":"first","affiliation":[{"name":"Surgical Oncology , Tata Medical Center , Newtown , Kolkata , West Bengal , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav","family":"Aggarwal","sequence":"additional","affiliation":[{"name":"Department of Uro-Oncology , Tata Medical Center , Newtown , Kolkata , West Bengal , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujoy","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Uro-Oncology , Tata Medical Center , Newtown , Kolkata , West Bengal , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Divya","family":"Midha","sequence":"additional","affiliation":[{"name":"Department of Onco-Pathology , Tata Medical Center , Newtown , Kolkata , West Bengal , India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2021,1,7]]},"reference":[{"key":"2021041608124800634_j_iss-2020-0022_ref_001_w2aab3b7c25b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Sadiq, M, Ahmad, I, Shuja, J, Ahmad, K. Primary Ewing sarcoma of the kidney: a case report and treatment review. CEN Case Rep 2017;6:132\u20135. https:\/\/doi.org\/10.1007\/s13730-017-0259-0.","DOI":"10.1007\/s13730-017-0259-0"},{"key":"2021041608124800634_j_iss-2020-0022_ref_002_w2aab3b7c25b1b6b1ab2b1b2Aa","doi-asserted-by":"crossref","unstructured":"Hakky, TS, Gonzalvo, AA, Lockhart, J, Rodriguez, AR. Primary Ewing sarcoma of the kidney: a symptomatic presentation and review of the literature. Ther Adv Urol.2013;5:153\u20139. https:\/\/doi.org\/10.1177\/1756287212471095.","DOI":"10.1177\/1756287212471095"},{"key":"2021041608124800634_j_iss-2020-0022_ref_003_w2aab3b7c25b1b6b1ab2b1b3Aa","doi-asserted-by":"crossref","unstructured":"Parham, DM, Roloson, GJ, Feely, M, Green, DM, Bridge, JA, Beckwith, JB, et al.. Primary malignant neuroepithelial tumors of the kidney: a clinicopathologic analysis of 146 adult and pediatric cases from the National Wilms\u2019 Tumor Study Group Pathology Center. Am J Surg Pathol 2001;25:133\u201346. https:\/\/doi.org\/10.1097\/00000478-200102000-00001.","DOI":"10.1097\/00000478-200102000-00001"},{"key":"2021041608124800634_j_iss-2020-0022_ref_004_w2aab3b7c25b1b6b1ab2b1b4Aa","doi-asserted-by":"crossref","unstructured":"Thyavihally, YB, Tongaonkar, HB, Gupta, S, Kurkure, PA, Amare, P, Muckaden, MA, et al.. Primitive neuroectodermal tumor of the kidney: a single institute series of 16 patients. Urology 2008;71:292\u20136. https:\/\/doi.org\/10.1016\/j.urology.2007.09.051.","DOI":"10.1016\/j.urology.2007.09.051"}],"container-title":["Innovative Surgical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/view\/journals\/iss\/5\/3-4\/article-p111.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/iss-2020-0022\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/iss-2020-0022\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T00:53:59Z","timestamp":1619052839000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/iss-2020-0022\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,1]]},"references-count":4,"journal-issue":{"issue":"3-4","published-online":{"date-parts":[[2020,10,29]]},"published-print":{"date-parts":[[2021,1,18]]}},"alternative-id":["10.1515\/iss-2020-0022"],"URL":"https:\/\/doi.org\/10.1515\/iss-2020-0022","relation":{},"ISSN":["2364-7485"],"issn-type":[{"value":"2364-7485","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,1]]}}}