{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T13:10:26Z","timestamp":1701781826088},"reference-count":4,"publisher":"Walter de Gruyter GmbH","issue":"2","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,5]]},"abstract":"Abstract<\/jats:title>\n \n Objectives<\/jats:title>\n The Kasabach\u2013Merritt syndrome (KMS) is characterized by the occurrence of hemangioendothelioma (giant hemangioma with thrombosis leading to thrombocytopenia), which can be associated with disseminated intravasal coagulation. Specific aim: Based on (i) selective references from the current scientific literature and derived recommendations as well as (ii) own experiences obtained in the diagnostic and perioperative management of a representative case from daily practice in abdominal surgery, the specific case undergoing elective cholecystectomy (CCE) in KMS is to be described by means of scientific case report.<\/jats:p>\n <\/jats:sec>\n \n Case presentation<\/jats:title>\n (Patient-, finding- and treatment-specific characteristics): \u2013 Medical history: 72-years old female patient with a known KMS of the left arm and upper thorax, recurrent thrombophlebitis of the left arm and thoracic veins, previous upper GI bleeding (Mallory-Weiss syndrome in 2006, chronic anemia in lack of vitamin B12, type-A gastritis, former bleeding complications after teeth extraction\/open appendectomy 1962\/Caesarean section 1968 with need of transfusion [60 red blood cell packages]), intraabdominal adhesions, hypothyreosis, initial liver cirrhosis. \u2013 Symptomatology: Characteristic for cholecystolithiasis (CCL). \u2013 Diagnostic: Abdominal ultrasound shows CCL, fibroscan does not confirm suspicious cirrhosis. Laboratory parameters showed: Activation of intravasal coagulation with elevated prothrombin fragments, D-dimers and reduced antiplasmin concentration. Accelerated fibrinolysis capacity; currently, no secondary thrombocytopenia or factor-13 decrease. In addition, fibrinogen concentration within normal range, no hint onto the manifestation of an aquired von-Willebrand\u2019s syndrome. \u2013 Diagnosis: Chronic fibrosing cholecystitis in CCL after former acute cholecystitis (3\u202fmonths ago) with indication for surgical intervention. \u2013 Therapy: Laparoscopic CCE including careful exploration of upper abdominal cavity for KMS manifestation (with no revision of bile duct) and peritoneal adhesiolysis (histological finding, chronic fibrosing cholecystitis with thickening of the wall of the gall bladder but no hint of malignancy) under perioperative prophylaxis with antibiotics and temporary cessation of platelet medication for 7\u202fd preoperatively, \u201cbridging\u201d with low molecular weight heparin (Clexane, 1 \u00d7 40\u202fmg\u202fs.c.; Sanofi-Aventis, Frankfurt\/Main, Germany); 1\u202fh preoperatively, 15\u201320\u202fmg\/kg body weight Cyclocapron i.v. (once again 6\u20138\u202fh postoperatively; thereafter, 500\u202fmg of Cyclocapron 4\u00d7\/d until the 3rd postoperative day). \u2013 Intraoperatively: Congestion of veins but not at the immediate surgical field (gall bladder, hepatic bed of the gall bladder, Calot\u2019s triangle). \u2013 Outcome: Uneventful, in particular, no (bleeding) complications.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n If surgical approach is indicated, the intervention should be thoroughly planned (in particular, under elective circumstances) with regard to hemangioma site and extension as well as distance to the surgical field and possible surgical alternative options (surgical access site, open\/laparoscopic approach etc.) to prevent \u2013 at the best possible rate \u2013 bleeding complications intra-\/postoperatively and, thus, to provide adequate patient safety.<\/jats:p>\n <\/jats:sec>","DOI":"10.1515\/iss-2022-0017","type":"journal-article","created":{"date-parts":[[2023,8,2]],"date-time":"2023-08-02T15:30:38Z","timestamp":1690990238000},"page":"113-117","source":"Crossref","is-referenced-by-count":0,"title":["Laparoscopic cholecystectomy for symptomatic cholecystolithiasis (CCL) in \u201cKasabach\u2013Merritt syndrome\u201d (KMS) (Kaposi-tumor like hemangioendothelioma with case-specific perioperative management)"],"prefix":"10.1515","volume":"8","author":[{"given":"Stephan","family":"Arndt","sequence":"first","affiliation":[{"name":"Department of General, Abdominal, Vascular and Transplant Surgery , University Hospital , Magdeburg , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cora","family":"Wex","sequence":"additional","affiliation":[{"name":"Department of General, Abdominal, Vascular and Transplant Surgery , University Hospital , Magdeburg , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inken","family":"H\u00e4usler-Pliske","sequence":"additional","affiliation":[{"name":"Department of General, Abdominal, Vascular and Transplant Surgery , University Hospital , Magdeburg , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u00f6rthe","family":"Jechorek","sequence":"additional","affiliation":[{"name":"Institute of Pathology, University Hospital , Magdeburg , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hardy","family":"Krause","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Department of General, Abdominal, Vascular and Transplant Surgery , University Hospital , Magdeburg , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zuhir","family":"Halloul","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Department of General, Abdominal, Vascular and Transplant Surgery , University Hospital , Magdeburg , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Meyer","sequence":"additional","affiliation":[{"name":"Department of General, Abdominal, Vascular and Transplant Surgery , University Hospital , Magdeburg , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2023,8,3]]},"reference":[{"key":"2023120512422733543_j_iss-2022-0017_ref_001","doi-asserted-by":"crossref","unstructured":"Kasabach, HH, Merritt, KK. Capillaryhaemangioma with extensive purpura. Am J Dis Child 1940;59:1063. https:\/\/doi.org\/10.1001\/archpedi.1940.01990160135009.","DOI":"10.1001\/archpedi.1940.01990160135009"},{"key":"2023120512422733543_j_iss-2022-0017_ref_002","doi-asserted-by":"crossref","unstructured":"Croteau, SE, Liang, MG, Kozakewich, HP, Alomari, AI, Fishman, SJ, Mulliken, JB, et al.. Kaposiform hemangioendothelioma: atypical features and risks of Kasabach-Merritt phenomenon in 107 referrals. J Pediatr 2013;162:142\u20137. https:\/\/doi.org\/10.1016\/j.jpeds.2012.06.044.","DOI":"10.1016\/j.jpeds.2012.06.044"},{"key":"2023120512422733543_j_iss-2022-0017_ref_003","doi-asserted-by":"crossref","unstructured":"Putra, J, Gupta, A. Kaposiform haemangioendothelioma: a review with emphasis on histological differential diagnosis. Pathology 2017;49:356\u201362. https:\/\/doi.org\/10.1016\/j.pathol.2017.03.001.","DOI":"10.1016\/j.pathol.2017.03.001"},{"key":"2023120512422733543_j_iss-2022-0017_ref_004","doi-asserted-by":"crossref","unstructured":"Mahajan, P, Margolin, J, Iacobas, I. Kasabach-Merritt phenomenon: classic presentation and management options. Clin Med Insights Blood Disord 2017;10:1179545X17699849. https:\/\/doi.org\/10.1177\/1179545x17699849.","DOI":"10.1177\/1179545X17699849"}],"container-title":["Innovative Surgical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/iss-2022-0017\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/iss-2022-0017\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T12:43:38Z","timestamp":1701780218000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/iss-2022-0017\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,1]]},"references-count":4,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,9,21]]},"published-print":{"date-parts":[[2023,12,5]]}},"alternative-id":["10.1515\/iss-2022-0017"],"URL":"https:\/\/doi.org\/10.1515\/iss-2022-0017","relation":{},"ISSN":["2364-7485"],"issn-type":[{"value":"2364-7485","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,1]]}}}