{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T15:14:52Z","timestamp":1792336492817,"version":"4.4.0"},"reference-count":21,"publisher":"Walter de Gruyter GmbH","issue":"2","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_iss-2023-0066_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Deep thermal injuries are among the most serious injuries in childhood, often resulting in scarring and\u00a0functional impairment. However, accurate assessment of burn depth by clinical judgment is challenging. Optical coherence tomography (OCT) provides structural images of the skin and can detect blood flow within the papillary plexus. In this study, we determined the depth of the capillary network in healthy and thermally injured skin and compared it with clinical assessment.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_iss-2023-0066_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>In 25 children between 7\u00a0months and 15 years of age (mean age 3.5 years (SD\u00b14.14)) with thermal injuries of the ventral thoracic wall, we determined the depth of the capillary network using OCT. Measurements were performed on healthy skin and at the center of the thermal injury (16 grade IIa, 9 grade IIb). Comparisons were made between healthy skin and thermal injury.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_iss-2023-0066_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The capillary network of the papillary plexus in healthy skin was detected at 0.33\u202fmm (SD\u00b10.06) from the surface. In grade IIb injuries, the depth of the capillary network was 0.36\u202fmm (SD\u00b10.06) and in grade IIa injuries 0.23\u202fmm (SD\u00b10.04) (Mann\u2013Whitney U test: p&lt;0.001). The overall prediction accuracy is 84\u202f%.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_iss-2023-0066_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>OCT can reliably detect and differentiate the depth of the capillary network in both healthy and burned skin. In clinical IIa wounds, the capillary network appears more superficial due to the loss of the epidermis, but it is still present in the upper layer, indicating a good prognosis for\u00a0spontaneous healing. In clinical grade IIb wounds, the papillary plexus was visualized deeper, which is a sign of impaired blood flow.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/iss-2023-0066","type":"journal-article","created":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T16:49:03Z","timestamp":1718124543000},"page":"83-91","source":"Crossref","is-referenced-by-count":2,"title":["Depth of intact vascular plexus\u00a0\u2013 visualized with optical coherence tomography\u00a0\u2013 correlates to burn depth in thoracic thermic injuries in children"],"prefix":"10.1515","volume":"9","author":[{"given":"Valerie","family":"Dalicho","sequence":"first","affiliation":[{"name":"Paediatric Burn Center L\u00fcbeck, Department of Paediatric Surgery , University Hospital L\u00fcbeck , L\u00fcbeck , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Straube","sequence":"additional","affiliation":[{"name":"Paediatric Burn Center L\u00fcbeck, Department of Paediatric Surgery , University Hospital L\u00fcbeck , L\u00fcbeck , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin","family":"Kelly","sequence":"additional","affiliation":[{"name":"Paediatric Burn Center L\u00fcbeck, Department of Paediatric Surgery , University Hospital L\u00fcbeck , L\u00fcbeck , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beke","family":"Larsen","sequence":"additional","affiliation":[{"name":"Paediatric Burn Center L\u00fcbeck, Department of Paediatric Surgery , University Hospital L\u00fcbeck , L\u00fcbeck , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutz","family":"W\u00fcnsch","sequence":"additional","affiliation":[{"name":"Paediatric Burn Center L\u00fcbeck, Department of Paediatric Surgery , University Hospital L\u00fcbeck , L\u00fcbeck , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3543-5974","authenticated-orcid":false,"given":"Judith","family":"Lindert","sequence":"additional","affiliation":[{"name":"Paediatric Burn Center L\u00fcbeck, Department of Paediatric Surgery , University Hospital L\u00fcbeck , L\u00fcbeck , Germany"},{"name":"Department of Paediatric Surgery , University Hospital Rostock Rostock , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2024,6,12]]},"reference":[{"key":"2024080106212726830_j_iss-2023-0066_ref_001","unstructured":"Association of the Scientific Medical Societies (AWMF). 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