{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T01:20:59Z","timestamp":1773278459569,"version":"3.50.1"},"reference-count":0,"publisher":"Walter de Gruyter GmbH","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    The present study was carried out to test the antibacterial effect of the body wall of the sea cucumber\n                    <jats:italic>Holothuria leucospilota<\/jats:italic>\n                    Brandt on\n                    <jats:italic>Streptococcus mutans<\/jats:italic>\n                    and\n                    <jats:italic>Streptococcus salivarius<\/jats:italic>\n                    .\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    After sampling sea cucumbers from the Persian Gulf, different extractions were prepared. Then, aqueous, phosphate-buffered saline (PBS, pH 7.8), chloroform, hexane and methanolic extracts from sea cucumber body wall were screened for antibacterial activity against pathogenic bacteria\n                    <jats:italic>S. mutans<\/jats:italic>\n                    and\n                    <jats:italic>S. salivarius<\/jats:italic>\n                    using the disk diffusion method.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    The PBS extract did not show any antibacterial or inhibitory activity; the chloroform extract, however, demonstrated high levels of antibacterial activity against\n                    <jats:italic>S. salivarius<\/jats:italic>\n                    while exhibiting low levels of activity against\n                    <jats:italic>S. mutans<\/jats:italic>\n                    . The hexane and methanolic extracts were found to show no antibacterial activity against\n                    <jats:italic>S. mutans<\/jats:italic>\n                    , but exhibited antibacterial activity against\n                    <jats:italic>S. salivarius.<\/jats:italic>\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    In conclusion, the results demonstrated the possibility of utilizing sea cucumbers as a cheap source of potential antibacterial agents and for treating odontogenic diseases.\n                  <\/jats:p>","DOI":"10.1515\/jbcpp-2013-0010","type":"journal-article","created":{"date-parts":[[2014,1,27]],"date-time":"2014-01-27T15:48:49Z","timestamp":1390837729000},"page":"367-373","source":"Crossref","is-referenced-by-count":17,"title":["Antibacterial activity of the body wall extracts of sea cucumber (Invertebrata; Echinodermata) on infectious oral streptococci"],"prefix":"10.1515","volume":"25","author":[{"given":"Negin","family":"Kiani","sequence":"first","affiliation":[{"name":"Faculty of Science, Department of Biology, University of Guilan, Rasht, Guilan, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Behrooz","family":"Heidari","sequence":"additional","affiliation":[{"name":"Faculty of Science, Department of Biology, University of Guilan, Rasht, Guilan, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehdi","family":"Rassa","sequence":"additional","affiliation":[{"name":"Faculty of Science, Department of Biology, University of Guilan, Rasht, Guilan, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahdi","family":"Kadkhodazadeh","sequence":"additional","affiliation":[{"name":"Dental Research Centre, Research Institute of Dental Sciences of Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bijan","family":"Heidari","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Department of Prosthodontics, Hamadan University of Medical Sciences, Hamedan, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2014,1,27]]},"container-title":["Journal of Basic and Clinical Physiology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/jbcpp-2013-0010\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/jbcpp-2013-0010\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T12:02:11Z","timestamp":1765540931000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/jbcpp-2013-0010\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,27]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2014,1,27]]},"published-print":{"date-parts":[[2014,11,1]]}},"alternative-id":["10.1515\/jbcpp-2013-0010"],"URL":"https:\/\/doi.org\/10.1515\/jbcpp-2013-0010","relation":{},"ISSN":["2191-0286","0792-6855"],"issn-type":[{"value":"2191-0286","type":"electronic"},{"value":"0792-6855","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1,27]]}}}