{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T09:35:09Z","timestamp":1776418509594,"version":"3.51.2"},"reference-count":46,"publisher":"Walter de Gruyter GmbH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,5,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jbcpp-2017-0176_s_999_w2aab3b7b6b1b6b1aab1c14b1Aa\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Ziziphus mauritiana<\/jats:italic>\n                      Lam. is a plant used in traditional medicine in Burkina Faso in the treatment of several diseases, of which diabetes is characterized by oxidative stress. The aim of this study was to evaluate the in vitro antioxidant potential of the extracts of leaves of this plant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2017-0176_s_998_w2aab3b7b6b1b6b1aab1c14b2Aa\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The crude hydroethanolic extract (HEE) of the leaves of\n                      <jats:italic>Z. mauritiana<\/jats:italic>\n                      and their partitionates in\n                      <jats:italic>n<\/jats:italic>\n                      -hexane, dichloromethane, and ethyl acetate, and in the residual aqueous solution (the F1, F2, F3, and F4 fractions, respectively) were first prepared. The content of polyphenols was determined and the antioxidant effects of the extracts were evaluated by their 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging activity, inhibition of lipid peroxidation (TBARS), and the ferric reducing antioxidant power (FRAP).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2017-0176_s_997_w2aab3b7b6b1b6b1aab1c14b3Aa\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The HEE as well as the F3 and F4 fractions were rich in polyphenols with contents between 58 and 84 mg equivalent gallic acid per 100 mg. The flavonoid content was 4 mg quercetin equivalents in the HEE and the F4 fraction. Except for the F1 fraction, the HEE and the other fractions showed significant DPPH scavenging activity (IC\n                      <jats:sub>50<\/jats:sub>\n                      between 8 and 12 \u03bcg\/mL). The IC\n                      <jats:sub>50<\/jats:sub>\n                      of TBARS by different extracts was in the range 1\u20135 \u03bcg\/mL, and the FRAP activity was 7\u201385 mg ascorbic acid equivalent per 100 mg. Total polyphenol content was highly correlated with the antioxidant activities.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2017-0176_s_996_w2aab3b7b6b1b6b1aab1c14b4Aa\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The HEE, F3, and F4 fractions were found to be the richest in polyphenols and had the best antioxidant activity. The antioxidant activity of the extracts of the leaves of\n                      <jats:italic>Z. mauritiana<\/jats:italic>\n                      is due to these polyphenolic compounds.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jbcpp-2017-0176","type":"journal-article","created":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T12:56:57Z","timestamp":1557147417000},"source":"Crossref","is-referenced-by-count":6,"title":["Antioxidant activity of crude ethanolic extract and fractions of\n                    <i>Ziziphus mauritiana<\/i>\n                    Lam. (Rhamnaceae) leaves from Burkina Faso"],"prefix":"10.1515","volume":"30","author":[{"given":"Estelle N.H.","family":"Youl","sequence":"first","affiliation":[{"name":"Laboratory of drug development , University Ouaga I Pr Joseph Ki-Zerbo , BP 958 Ouagadougou 09 , Burkina Faso , Phone: (+226) 78820311"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cyrille A.P.","family":"Ou\u00e9draogo","sequence":"additional","affiliation":[{"name":"Laboratory of Drug Development , University Ouaga I Pr Joseph Ki-Zerbo , Ouagadougou , Burkina Faso"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moustapha","family":"Gambo","sequence":"additional","affiliation":[{"name":"Laboratory of Drug Development , University Ouaga I Pr Joseph Ki-Zerbo , Ouagadougou , Burkina Faso"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moussa","family":"Ou\u00e9draogo","sequence":"additional","affiliation":[{"name":"Laboratory of Drug Development , University Ouaga I Pr Joseph Ki-Zerbo , Ouagadougou , Burkina Faso"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Kiendreb\u00e9ogo","sequence":"additional","affiliation":[{"name":"Laboratory of Biochemistry and Chemistry Applied , University Ouaga I Pr Joseph Ki-Zerbo , Ouagadougou , Burkina Faso"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aristide","family":"Traor\u00e9","sequence":"additional","affiliation":[{"name":"Research Institute for Health Sciences , Ouagadougou , Burkina Faso"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Innocent Pierre","family":"Guissou","sequence":"additional","affiliation":[{"name":"Laboratory of Drug Development , University Ouaga I Pr Joseph Ki-Zerbo , Ouagadougou , Burkina Faso"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2019,5,4]]},"reference":[{"key":"2025121209181536992_j_jbcpp-2017-0176_ref_001_w2aab3b7b6b1b6b1ab2b2b1Aa","doi-asserted-by":"crossref","unstructured":"Pincemail J, Bonjean K, Cayeux K, Defraigne JO. 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