{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T19:50:15Z","timestamp":1783021815287,"version":"3.54.6"},"reference-count":12,"publisher":"Walter de Gruyter GmbH","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,12,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We report a 26-year-old male patient diagnosed with extensively drug-resistant pulmonary tuberculosis presenting with reversible bilateral toxic optic neuropathy induced by the use of linezolid along with high-dose isoniazid. The case emphasizes the importance of recognizing toxic optic neuritis in patients on antitubercular therapy. Prompt recognition and treatment of such adverse drug reactions will reduce the associated morbidity.<\/jats:p>","DOI":"10.1515\/jbcpp-2018-0007","type":"journal-article","created":{"date-parts":[[2018,12,22]],"date-time":"2018-12-22T07:01:14Z","timestamp":1545462074000},"page":"139-140","source":"Crossref","is-referenced-by-count":6,"title":["Drug-induced optic neuropathy in a case of extensively drug-resistant pulmonary tuberculosis"],"prefix":"10.1515","volume":"30","author":[{"given":"Proteesh","family":"Rana","sequence":"first","affiliation":[{"name":"Dr Ram Manohar Lohia Hospital and Post Graduate Institute of Medical Education and Research , Department of Pharmacology , New Delhi , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vandana","family":"Roy","sequence":"additional","affiliation":[{"name":"Maulana Azad Medical College , Department of Pharmacology , New Delhi , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamshed","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Maulana Azad Medical College , Department of Pharmacology , New Delhi , India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2018,9,3]]},"reference":[{"key":"2025121209214167586_j_jbcpp-2018-0007_ref_001_w2aab3b7b6b1b6b1ab1b4b1Aa","doi-asserted-by":"crossref","unstructured":"Sharma P, Sharma R. Toxic optic neuropathy. Indian J Ophthalmol 2011;59:137\u201341.2135028310.4103\/0301-4738.77035","DOI":"10.4103\/0301-4738.77035"},{"key":"2025121209214167586_j_jbcpp-2018-0007_ref_002_w2aab3b7b6b1b6b1ab1b4b2Aa","unstructured":"The use of the WHO-UMC system for standardised case causality assessment. Available at: http\/\/www.who-umc.org\/Graphics\/24734.pdf. Accessed: 4 Aug 2016."},{"key":"2025121209214167586_j_jbcpp-2018-0007_ref_003_w2aab3b7b6b1b6b1ab1b4b3Aa","doi-asserted-by":"crossref","unstructured":"Naranjo C, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239\u201345.724950810.1038\/clpt.1981.154","DOI":"10.1038\/clpt.1981.154"},{"key":"2025121209214167586_j_jbcpp-2018-0007_ref_004_w2aab3b7b6b1b6b1ab1b4b4Aa","doi-asserted-by":"crossref","unstructured":"Tripathi KD. Essentials of medical pharmacology. In: Macrolide, lincosamide, glycopeptide and other antibacterial antibiotics, 7th ed. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd, 2013:758.","DOI":"10.5005\/jp\/books\/12021_58"},{"key":"2025121209214167586_j_jbcpp-2018-0007_ref_005_w2aab3b7b6b1b6b1ab1b4b5Aa","unstructured":"World Health Organization. Guidelines for the programmatic management of drug-resistant tuberculosis: emergency update 2008. Available at: http:\/\/apps.who.int\/iris\/bitstream\/ 10665\/43965\/1\/9789241547581_eng.pdf. Accessed: 30 Jul 2016."},{"key":"2025121209214167586_j_jbcpp-2018-0007_ref_006_w2aab3b7b6b1b6b1ab1b4b6Aa","doi-asserted-by":"crossref","unstructured":"Javaheri M, Khurana RN, O\u2019Hearn TM, Lai MM, Sadun AA. Linezolid-induced optic neuropathy: a mitochondrial disorder? Br J Ophthalmol 2007;91:111\u20135.1717912510.1136\/bjo.2006.102541","DOI":"10.1136\/bjo.2006.102541"},{"key":"2025121209214167586_j_jbcpp-2018-0007_ref_007_w2aab3b7b6b1b6b1ab1b4b7Aa","unstructured":"Tripathi KD. Essentials of medical pharmacology. In: Antitubercular drugs, 7th ed. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd, 2013:766\u20137."},{"key":"2025121209214167586_j_jbcpp-2018-0007_ref_008_w2aab3b7b6b1b6b1ab1b4b8Aa","doi-asserted-by":"crossref","unstructured":"Kulkarni HS, Keskar VS, Bavdekar SB, Gabhale Y. Bilateral optic neuritis due to Isoniazid (INH). Indian Paediatr 2010;47:533\u20135.10.1007\/s13312-010-0083-5","DOI":"10.1007\/s13312-010-0083-5"},{"key":"2025121209214167586_j_jbcpp-2018-0007_ref_009_w2aab3b7b6b1b6b1ab1b4b9Aa","doi-asserted-by":"crossref","unstructured":"Lim SA. Ethambutol-associated optic neuropathy. Ann Acad Med Singapore 2006;35:274\u20138.16710500","DOI":"10.47102\/annals-acadmedsg.V35N4p274"},{"key":"2025121209214167586_j_jbcpp-2018-0007_ref_010_w2aab3b7b6b1b6b1ab1b4c10Aa","unstructured":"Sweetman SC, editor. Martindale. The complete drug reference, 35th ed. London: Pharmaceutical Press, 2007."},{"key":"2025121209214167586_j_jbcpp-2018-0007_ref_011_w2aab3b7b6b1b6b1ab1b4c11Aa","doi-asserted-by":"crossref","unstructured":"Magazine R, Pal M, Chogtu B, Nayak V. Capreomycin-induced optic neuritis in a case of multidrug resistant pulmonary tuberculosis. Indian J Pharmacol 2010;42:247\u20138.10.4103\/0253-7613.68436","DOI":"10.4103\/0253-7613.68436"},{"key":"2025121209214167586_j_jbcpp-2018-0007_ref_012_w2aab3b7b6b1b6b1ab1b4c12Aa","doi-asserted-by":"crossref","unstructured":"Kulkarni K, Del Priore LV. Linezolid induced toxic optic neuropathy. Br J Ophthalmol 2005;89:1664\u20135.1629915610.1136\/bjo.2005.074237","DOI":"10.1136\/bjo.2005.074237"}],"container-title":["Journal of Basic and Clinical Physiology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.degruyter.com\/view\/j\/jbcpp.2019.30.issue-1\/jbcpp-2018-0007\/jbcpp-2018-0007.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/jbcpp-2018-0007\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/jbcpp-2018-0007\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T12:18:59Z","timestamp":1765541939000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1515\/jbcpp-2018-0007\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,3]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,9,6]]},"published-print":{"date-parts":[[2018,12,19]]}},"alternative-id":["10.1515\/jbcpp-2018-0007"],"URL":"https:\/\/doi.org\/10.1515\/jbcpp-2018-0007","relation":{},"ISSN":["2191-0286","0792-6855"],"issn-type":[{"value":"2191-0286","type":"electronic"},{"value":"0792-6855","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9,3]]}}}