{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T22:58:10Z","timestamp":1781305090229,"version":"3.54.1"},"reference-count":23,"publisher":"Walter de Gruyter GmbH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,5,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jbcpp-2018-0173_s_999_w2aab3b7c49b1b6b1aab1c14b1Aa\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Typha capensis<\/jats:italic>\n                      is one of the medicinal plants commonly used to manage male fertility problems. The objective of the present study was to assess its fertility-promoting effects in a rat model of cadmium-induced infertility.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2018-0173_s_998_w2aab3b7c49b1b6b1aab1c14b2Aa\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A total of 30 male Wister rats were randomly divided into five groups of six animals each. Animals of group I, which served as control, were administered with cadmium chloride (CdCl\n                      <jats:sub>2<\/jats:sub>\n                      ; 2.5 mg\/kg) and normal saline (2 mL\/kg). Group II was served with 0.5 mL normal saline only. Animals of groups III\u2013V were treated with CdCl\n                      <jats:sub>2<\/jats:sub>\n                      (2.5 mg\/kg) plus\n                      <jats:italic>T. capensis<\/jats:italic>\n                      extract at doses of 100, 200, and 400 mg\/kg, respectively. Animals were sacrificed under sedation. Testes and epididymal weights and sperm count were determined. Histological assessment of the testes was conducted.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2018-0173_s_997_w2aab3b7c49b1b6b1aab1c14b3Aa\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:italic>T. capensis<\/jats:italic>\n                      at any dose did not improve (p &gt; 0.05) testicular and epididymal weights compared with those of the CdCl\n                      <jats:sub>2<\/jats:sub>\n                      -exposed control group. Histology revealed moderate necrosis in the same group.\n                      <jats:italic>T. capensis<\/jats:italic>\n                      modestly increased the sperm count by 14%, 31%, and 35%, for groups treated with the extract at doses 100, 200, and 400 mg\/kg, respectively, when compared with the CdCl\n                      <jats:sub>2<\/jats:sub>\n                      control group, although the differences were not significant statistically (p &gt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2018-0173_s_996_w2aab3b7c49b1b6b1aab1c14b4Aa\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Results of our study demonstrated that\n                      <jats:italic>T. capensis<\/jats:italic>\n                      can neither offer protective effects against oxidative stress nor promote fertility in an animal model of cadmium-induced infertility.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jbcpp-2018-0173","type":"journal-article","created":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T12:56:57Z","timestamp":1557147417000},"source":"Crossref","is-referenced-by-count":2,"title":["The protective effect of aqueous extract of\n                    <i>Typha capensis<\/i>\n                    rhizomes on cadmium-induced infertility in rats"],"prefix":"10.1515","volume":"30","author":[{"given":"Mavuto Masopera","family":"Gondwe","sequence":"first","affiliation":[{"name":"Walter Sisulu University , Human Biology , Private Bag X1 Mthatha 5117 , South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andile","family":"Mpungose","sequence":"additional","affiliation":[{"name":"Walter Sisulu University , Human Biology , Private Bag X1 Mthatha 5117 , South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davie Rexon","family":"Kamadyaapa","sequence":"additional","affiliation":[{"name":"Walter Sisulu University , Human Biology , Private Bag X1 Mthatha 5117 , South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathulo","family":"Shauli","sequence":"additional","affiliation":[{"name":"Walter Sisulu University , Human Biology , Private Bag X1 Mthatha 5117 , South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene","family":"Ndebia","sequence":"additional","affiliation":[{"name":"Walter Sisulu University , Human Biology , Private Bag X1 Mthatha 5117 , South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constance","family":"Sewani-Rusike","sequence":"additional","affiliation":[{"name":"Walter Sisulu University , Human Biology , Private Bag X1 Mthatha 5117 , South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jehu","family":"Iputo","sequence":"additional","affiliation":[{"name":"Walter Sisulu University , Human Biology , Private Bag X1 Mthatha 5117 , South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adebola","family":"Oyedeji","sequence":"additional","affiliation":[{"name":"Walter Sisulu University , Chemistry , Private Bag X1 Mthatha 5117 , South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2019,5,4]]},"reference":[{"key":"2025121209255545925_j_jbcpp-2018-0173_ref_001_w2aab3b7c49b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Sharlip ID, Jarow JP, Belker AM, Lipshultz LI, Sigman M, Thomas AJ, et al. 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