{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T18:36:30Z","timestamp":1785090990959,"version":"3.55.0"},"reference-count":12,"publisher":"Walter de Gruyter GmbH","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,11,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jbcpp-2019-0250_s_999_w2aab3b8c41b1b7b1aab1c14b1Aa\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>It was reported that hemodialysis (HD) with either a new or reused dialyzer raises medical problems that require therapeutic regimens. This study aimed to investigate the medical problems and their management in patients undergoing HD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2019-0250_s_998_w2aab3b8c41b1b7b1aab1c14b2Aa\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study was conducted by prospectively observing patients with chronic kidney disease undergoing HD. The incidence of medical problems and the treatment given were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2019-0250_s_997_w2aab3b8c41b1b7b1aab1c14b3Aa\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 351 cases of HD, medical problems occurred in 15.7% of cases, including hypotension as the most dominant, followed by muscle cramps, shivering, headache, asphyxia, fever, chest pain, and pruritus. Hypotension was ameliorated with intravenous 40% dextrose and normal saline. Muscle cramps were overcome with 40% dextrose, normal saline, methampyrone, and calcium gluconate. Shivering was managed by warming the patients followed by intravenous methampyrone, 40% dextrose, and normal saline. Meanwhile, headache was reduced by paracetamol or intravenous methampyrone and 40% dextrose. Fever was treated by intravenous methampyrone or oral paracetamol. Pruritus was managed by intravenous dexamethasone and diphenhydramine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2019-0250_s_996_w2aab3b8c41b1b7b1aab1c14b4Aa\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Medical problems occurring during HD are prevalent and need immediate therapy. Pharmacists and clinicians should work in collaboration to improve the patients\u2019 quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jbcpp-2019-0250","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T04:02:53Z","timestamp":1574222573000},"source":"Crossref","is-referenced-by-count":6,"title":["Medical problems in patients with chronic kidney disease undergoing hemodialysis and their therapy"],"prefix":"10.1515","volume":"30","author":[{"given":"Budi","family":"Suprapti","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacy , Faculty of Pharmacy Airlangga University , Kampus C, UNAIR, Jl. Mulyorejo , Surabaya 60115 , Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenny Putri","family":"Nilamsari","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy , Faculty of Pharmacy Airlangga University , Surabaya , Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Rachmania","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy , Faculty of Pharmacy Airlangga University , Surabaya , Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Widodo","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Internal Medicine , Dr. Soetomo Teaching Hospital Surabaya , Surabaya , Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Alderman","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy , Faculty of Pharmacy Airlangga University , Kampus C, UNAIR, Jl. Mulyorejo , Surabaya 60115 , Indonesia"},{"name":"School of Pharmacy and Medical Sciences , University of South Australia , Adelaide, South Australia , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2019,11,20]]},"reference":[{"key":"2025121209201343238_j_jbcpp-2019-0250_ref_001_w2aab3b8c41b1b7b1ab2b1b1Aa","unstructured":"Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, Jameson JL. Renal disease. Harrison\u2019s manual of medicine, 16th ed. New York: McGraw Hill, 2005:699\u2013708."},{"key":"2025121209201343238_j_jbcpp-2019-0250_ref_002_w2aab3b8c41b1b7b1ab2b1b2Aa","unstructured":"Bakri S. Deteksi Dini dan Upaya-Upaya Pencegahan Progresivitas Penyakit Ginjal Kronik: Supplement, vol. 26, no. 3, July-September 2005, Depkes RI, 2007. Jumlah Penderita Penyakit Ginjal. Available at: www.depkes.go.ac. 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