{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T14:02:03Z","timestamp":1785592923865,"version":"3.56.0"},"reference-count":36,"publisher":"Walter de Gruyter GmbH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jbcpp-2020-0222_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      The role of aqueous extract of\n                      <jats:italic>Adansonia digitata<\/jats:italic>\n                      was investigated against cadmium chloride-induced testicular damage in Wistar Rats.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2020-0222_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Thirty (30) male Wistar Rats weighing (150\u2013170) were divided into six groups (n=5). Group A served as control and received oral administration of phosphate buffer saline; group B received 800\u00a0mg\/kg\n                      <jats:italic>A.\u00a0digitata<\/jats:italic>\n                      only; group C were injected intraperitoneally with single dose 2\u00a0mg\/kg\u00a0b.w cadmium chloride; group D were injected intraperitoneally with single dose 2\u00a0mg\/kg\u00a0b.w cadmium chloride and treated with 800\u00a0mg\/kg aqueous extract of\n                      <jats:italic>A.\u00a0digitata<\/jats:italic>\n                      ; group E received 300\u00a0mg\/kg vitamin E only; group F were injected intraperitoneally with single dose 2\u00a0mg\/kg\u00a0b.w cadmium chloride and treated with 300\u00a0mg\/kg vitamin E. After 21\u00a0days, the animals were sacrificed by cervical dislocation, the testes were excised fixed in Bouins fluids for histological analysis and the other homogenized in 5% sucrose solution for determination of tissue malondialdehyde (MDA) and antioxidant enzyme activity, biochemical assay.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2020-0222_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The group treated with cadmium chloride plus\n                      <jats:italic>A.\u00a0digitata<\/jats:italic>\n                      caused significant decrease in MDA levels with significant increase (p&lt;0.05) in antioxidant activities and biochemical enzymes when compared to cadmium chloride only group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2020-0222_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Aqueous extract of\n                      <jats:italic>A.\u00a0digitata<\/jats:italic>\n                      appears to have ameliorative effect against cadmium chloride-induced testicular damage. This could be attributed to the presence of polyphenolic compound.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jbcpp-2020-0222","type":"journal-article","created":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T17:58:28Z","timestamp":1615485508000},"page":"347-353","source":"Crossref","is-referenced-by-count":2,"title":["Aqueous extract of\n                    <i>Adansonia digitata<\/i>\n                    prevents Cadmium Chloride-induced testicular damage in Wistar Rats"],"prefix":"10.1515","volume":"33","author":[{"given":"Babatunde Joseph","family":"Dare","sequence":"first","affiliation":[{"name":"Department of Anatomy , Osun State University , Osogbo , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6327-8435","authenticated-orcid":false,"given":"Olugbemi Tope","family":"Olaniyan","sequence":"additional","affiliation":[{"name":"Laboratory for Reproductive Biology and Developmental Programming, Department of Physiology, Edo State University , Uzairue , Edo State , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oluwafemi Isaac","family":"Oyeniyi","sequence":"additional","affiliation":[{"name":"Department of Anatomy , Bingham University , Karu , Nasarawa State , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria Enevwo","family":"Okotie","sequence":"additional","affiliation":[{"name":"Department of Physiology , University of Ibadan , Ibadan , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismail Adetayo","family":"Lawal","sequence":"additional","affiliation":[{"name":"Department of Anatomy , Alhikmah University , Ilorin , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olugbenga","family":"Eweoya","sequence":"additional","affiliation":[{"name":"School of Medicine and Allied Health Sciences, University of the Gambia , Banjul , The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2021,3,11]]},"reference":[{"key":"2025121209185723829_j_jbcpp-2020-0222_ref_001","doi-asserted-by":"crossref","unstructured":"Kara, H, Cevik, A, Konar, V, Dayangac, A, Yilmaz, M. 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