{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T01:56:15Z","timestamp":1784426175230,"version":"3.55.0"},"reference-count":26,"publisher":"Walter de Gruyter GmbH","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jbcpp-2025-0117_abs_001\">\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Necrotizing fasciitis (NF) is a rare but potentially fatal infection, involving the subcutaneous tissue and fascia. The incidence of NF worldwide ranges from 0.30 to 15 cases per 100,000 populations and mortality remains high at 25\u202f%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2025-0117_abs_002\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To classify severity of necrotizing fasciitis and assess the prognosis of necrotizing fasciitis using the LRINEC Scoring system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2025-0117_abs_003\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A thorough history and detailed clinical examination was done. Patient underwent necessary investigations like hemoglobulin, total leukocyte count, serum sodium, serum creatinine, random blood sugar, and C-reactive protein. Based on the investigations, two groups were formulated, LRINEC score &lt;6 (low risk) and\u00a0\u22656 (high risk). Then prognosis was assessed. The results were compared between the two groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2025-0117_abs_004\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In our study, a total of 124 patients were included with 62 of them with LRINEC score of &lt;6 and 62 patients with LRINEC score\u00a0\u22656. The sensitivity and specificity for predicting the septic shock and mortality with LRINEC score is 94\u202f% and 70\u202f% and 94\u202f% and 71\u202f%, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2025-0117_abs_005\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>LRINEC score is a simple clinical tool for predicting the prognostic outcomes in patients with necrotizing fasciitis. LRINEC score of\u00a0\u22656 have poorer prognosis in the form septic shock and eventual mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jbcpp-2025-0117","type":"journal-article","created":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T00:12:01Z","timestamp":1765843921000},"page":"133-138","source":"Crossref","is-referenced-by-count":1,"title":["A prospective study to assess the prognosis of patients with necrotizing fasciitis using laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system in a tertiary care hospital"],"prefix":"10.1515","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7646-2741","authenticated-orcid":false,"given":"Rekha","family":"Walwekar","sequence":"first","affiliation":[{"name":"Department of Pharmacology , Jagadguru Gangadhar Mahaswamigalu Moorusaviramath Medical College , Hubballi , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vignesh","family":"Ramalingam","sequence":"additional","affiliation":[{"name":"Department of General Surgery , Trichy SRM Medical College Hospital and Research Centre , Trichy , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun","family":"Walwekar","sequence":"additional","affiliation":[{"name":"Department of General Surgery , Karnataka Medical College and Research Institute , Hubballi , India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2025,12,17]]},"reference":[{"key":"2026041004402359276_j_jbcpp-2025-0117_ref_001","unstructured":"Puvanendran, R, Huey, JC, Pasupathy, S. 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Risk Manag Healthc Policy 2020;13:1613\u201324. https:\/\/doi.org\/10.2147\/RMHP.S263974.","DOI":"10.2147\/RMHP.S263974"},{"key":"2026041004402359276_j_jbcpp-2025-0117_ref_004","doi-asserted-by":"crossref","unstructured":"Study, OG, Kaul, R, McGeer, A, Low, DE, Green, K, Schwartz, B, et al.. Population-based surveillance for group A streptococcal necrotizing fasciitis: clinical features, prognostic indicators, and microbiologic analysis of seventy-seven cases. Am J Med 1997;103:18\u201324. https:\/\/doi.org\/10.1016\/s0002-9343(97)00160-5.","DOI":"10.1016\/S0002-9343(97)00160-5"},{"key":"2026041004402359276_j_jbcpp-2025-0117_ref_005","doi-asserted-by":"crossref","unstructured":"Chen, LL, Fasolka, B, Treacy, C. Necrotizing fasciitis: a comprehensive review. 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Crit Care Med 2004;32:1535\u201341. https:\/\/doi.org\/10.1097\/01.ccm.0000129486.35458.7d.","DOI":"10.1097\/01.CCM.0000129486.35458.7D"},{"key":"2026041004402359276_j_jbcpp-2025-0117_ref_018","doi-asserted-by":"crossref","unstructured":"Fernando, SM, Tran, A, Cheng, W, Rochwerg, B, Kyeremanteng, K, Seely, AJ, et al.. Necrotizing soft tissue infection: diagnostic accuracy of physical examination, imaging, and LRINEC score: a systematic review and meta-analysis. Ann Surg 2019;1:58\u201365. https:\/\/doi.org\/10.1097\/sla.0000000000002774.","DOI":"10.1097\/SLA.0000000000002774"},{"key":"2026041004402359276_j_jbcpp-2025-0117_ref_019","doi-asserted-by":"crossref","unstructured":"Bechar, J, Sepehripour, S, Hardwicke, J, Filobbos, G. Laboratory risk indicator for necrotising fasciitis (LRINEC) score for the assessment of early necrotising fasciitis: a systematic review of the literature. 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