{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T12:02:21Z","timestamp":1780315341588,"version":"3.54.1"},"reference-count":55,"publisher":"Walter de Gruyter GmbH","issue":"3","funder":[{"name":"Comune di Pagani; Sinergie in Rete"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jbcpp-2025-0195_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Evaluate associations between serum copper (Cu), rubidium (Rb), selenium (Se), strontium (Sr), and zinc (Zn) and psychophysical health in adults from Italy\u2019s Sarno River Basin within the 2025\u00a0PREVES-STOP program.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2025-0195_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Adults aged 30\u201365 completed validated questionnaires plus clinical evaluation and blood sampling. Elements were quantified by collision\/reaction-cell inductively coupled plasma mass spectrometry (ICP-MS). Associations were evaluated using Spearman and partial Spearman correlations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2025-0195_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Significant associations included Zn and Rb associated with lower odds (odds ratio, OR) of severe fatigue\u00a0\u2013 Recognizing and Estimating Signs of Tiredness (REST): Zn OR=0.38, 95\u202f% confidence interval (CI) 0.21\u20130.68, q=0.02; Rb OR=0.33, 95\u202f% CI 0.15\u20130.71, q=0.03\u00a0\u2013\u00a0while Sr was associated with higher well-being\u00a0\u2013\u00a0the World Health Organization-5 Well-Being Index (WHO-5) OR=1.36, 95\u202f% CI 1.12\u20131.65, q=0.02.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2025-0195_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Findings support broader trace-element panels to inform psychophysical and cardiometabolic risk beyond classical toxic metals, complementing prior PREVES-STOP evidence on lead (Pb) and cadmium (Cd). Further investigation is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jbcpp-2025-0195","type":"journal-article","created":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T15:00:35Z","timestamp":1767452435000},"page":"229-241","source":"Crossref","is-referenced-by-count":1,"title":["Serum copper, rubidium, selenium, strontium, and zinc and psychophysical health in adults of the Sarno river Basin: PREVES-STOP 2025 community biomonitoring results"],"prefix":"10.1515","volume":"37","author":[{"given":"Luca","family":"Scafuri","sequence":"first","affiliation":[{"name":"Oncology Unit , \u201cAndrea Tortora\u201d Hospital , ASL Salerno , Italy"},{"name":"Associazione O.R.A. 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