{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T12:07:13Z","timestamp":1780315633632,"version":"3.54.1"},"reference-count":35,"publisher":"Walter de Gruyter GmbH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jbcpp-2025-0200_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess the efficacy and safety of Flower Pollen Extract with Vitamins (PEV) in improving urinary and sexual function in men diagnosed with chronic prostatitis\u00a0(CP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2025-0200_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective controlled study was conducted involving 145 men with CP. Participants were divided into two groups: the intervention group received PEV (n=71) and the control group received ibuprofen (n=74). Clinical and functional outcomes were evaluated at baseline and at 1, 3, and 12\u00a0months post-treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2025-0200_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Both groups exhibited comparable baseline characteristics. At 3\u00a0months, the PEV group demonstrated significantly greater improvement in IPSS (9.4\u00a0\u00b1\u00a02.7 vs. 10.3\u00a0\u00b1\u00a02.6, p=0.04), NIH-CPSI (11.5\u00a0\u00b1\u00a03.7 vs. 13.6\u00a0\u00b1\u00a04.2, p=0.002), and IIEF-5 (19.8\u00a0\u00b1\u00a03.6 vs. 17.7\u00a0\u00b1\u00a03.3, p&lt;0.001). These benefits were maintained and further enhanced at 12\u00a0months, with mean IPSS 7.6\u00a0\u00b1\u00a02.1, NIH-CPSI 6.5\u00a0\u00b1\u00a02.4, and IIEF-5 21.6\u00a0\u00b1\u00a03.3 in the PEV group (all p&lt;0.005). No significant differences were observed in\u00a0Qmax.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jbcpp-2025-0200_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Long-term PEV therapy significantly improves urinary and sexual function in men with CP compared with ibuprofen treatment, demonstrating sustained, time-dependent efficacy and excellent safety.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jbcpp-2025-0200","type":"journal-article","created":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T04:39:41Z","timestamp":1766637581000},"page":"223-228","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of flower pollen extract with vitamins in improving urinary and sexual function in patients with chronic prostatitis: a retrospective study"],"prefix":"10.1515","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9934-4011","authenticated-orcid":false,"given":"Carlo","family":"Giulioni","sequence":"first","affiliation":[{"name":"Department of Urology , 47131 Casa di Cura Villa Igea , Ancona , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Maurizi","sequence":"additional","affiliation":[{"name":"Internal Medicine Unit Jesi , Jesi , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Falsetti","sequence":"additional","affiliation":[{"name":"Department of Precision and Regenerative Medicine and Ionian Area-Urology, Division of Urology, Andrology and Kidney Transplantation Unit , University of Bari \u201cAldo Moro\u201d , Bari , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felice","family":"Crocetto","sequence":"additional","affiliation":[{"name":"Department of Neurosciences and Reproductive Sciences and Odontostomatology , University of Naples \u201cFederico II\u201d , Naples , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Cafarelli","sequence":"additional","affiliation":[{"name":"Department of Urology , 47131 Casa di Cura Villa Igea , Ancona , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2025,12,25]]},"reference":[{"key":"2026060111144407589_j_jbcpp-2025-0200_ref_001","doi-asserted-by":"crossref","unstructured":"Collins, MM, Stafford, RS, O\u2019Leary, MP, Barry, MJ. 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