{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T17:20:28Z","timestamp":1780593628951,"version":"3.54.1"},"reference-count":14,"publisher":"Walter de Gruyter GmbH","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,6,1]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:bold>\n : Conventional plant-based therapies act as an important therapeutic tool for the treatment of worm infections all over the world and continuous evaluation of medicinal plants to find new potential lead compounds should be carried out.\n <\/jats:p>\n \n Methods<\/jats:bold>\n :\n In-vitro<\/jats:italic>\n analysis was conducted to evaluate the probable anthelmintic effect of crude aqueous and hydroalcoholic extracts of\n Ananas sativus<\/jats:italic>\n leaves\n , Erythrina variegata<\/jats:italic>\n barks and\n Alocasia indica<\/jats:italic>\n rootstocks, against adult\n Paramphistomum cervi<\/jats:italic>\n (Trematoda) and\n Haemonchus contortus<\/jats:italic>\n (Nematode).\n <\/jats:p>\n \n Results<\/jats:bold>\n : Among all three concentrations (25, 50, and 100 mg\/mL), the hydroalcoholic leaf extract of\n A. sativus<\/jats:italic>\n exhibited paralysis and death time ranged between 7.26 to 26.76 min and 15.40 to 35.55 min respectively for\n P. cervi<\/jats:italic>\n while that for\n H. contortus<\/jats:italic>\n was 14.70 to 42.43 min and 23.43 to 56.34 min, respectively. Moreover, aqueous extract exhibited paralysis and death time ranged between 7.66 to 28.72 min and 18.30 to 33.00 min, respectively, for\n P. cervi<\/jats:italic>\n whereas paralysis and death time ranged between 23.34 to 37.88 min and 31.08 to 58.30 min respectively for\n H. contortus<\/jats:italic>\n . Both extracts of\n E. variegata<\/jats:italic>\n bark and\n A. indica<\/jats:italic>\n tuber showed comparatively less significant anthelmintic activity. All results were statistically significant (p<0.001).\n <\/jats:p>\n \n Conclusions<\/jats:bold>\n :\n A. sativus<\/jats:italic>\n leaf displayed favorable anthelmintic activity on both\n P. cervi<\/jats:italic>\n and\n H. contortus<\/jats:italic>\n , whereas\n E. variegata<\/jats:italic>\n barks and\n A. indica<\/jats:italic>\n rootstocks showed insignificant result.\n <\/jats:p>","DOI":"10.1515\/jcim-2014-0059","type":"journal-article","created":{"date-parts":[[2015,4,13]],"date-time":"2015-04-13T07:59:52Z","timestamp":1428911992000},"page":"171-174","source":"Crossref","is-referenced-by-count":12,"title":["In-vitro<\/i>\n anthelmintic activity of three Bangladeshi plants against\n Paramphistomum cervi<\/i>\n and\n Haemonchus contortus<\/i>"],"prefix":"10.1515","volume":"12","author":[{"given":"Md. Khirul","family":"Islam","sequence":"first","affiliation":[{"name":"Pharmacy Discipline, Life Science School, Khulna University, Khulna, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md. Afjalus","family":"Siraj","sequence":"additional","affiliation":[{"name":"Pharmacy Discipline, Life Science School, Khulna University, Khulna, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asit Baron","family":"Sarker","sequence":"additional","affiliation":[{"name":"Pharmacy Discipline, Life Science School, Khulna University, Khulna, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjib","family":"Saha","sequence":"additional","affiliation":[{"name":"Pharmacy Discipline, Life Science School, Khulna University, Khulna, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imran","family":"Mahmud","sequence":"additional","affiliation":[{"name":"Pharmacy Discipline, Life Science School, Khulna University, Khulna, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md. Mustafizur","family":"Rahman","sequence":"additional","affiliation":[{"name":"Pharmacy Discipline, Life Science School, Khulna University, Khulna, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2015,4,11]]},"reference":[{"key":"2025121209161364815_CIT0001_w2aab2b8c25b1b7b1ab2b1b1Aa","first-page":"243","article-title":"Bromelain: A literature review and discussion of its therapeutic applications","volume":"1","year":"1996","journal-title":"Altern Med Rev"},{"key":"2025121209161364815_CIT0002_w2aab2b8c25b1b7b1ab2b1b2Aa","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1023\/A:1012794505897","article-title":"Small bowel review normal physiology. 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