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Women are more likely to develop osteoporosis than men due to reduction in estrogen during menopause which leads to decline in bone formation and increase in bone resorption activity. Estrogen is able to suppress the production of proinflammatory cytokines like interleukin (IL)-1, IL-6, IL-7 and tumor necrosis factor (TNF-\u03b1). This is why these cytokines are elevated in postmenopausal women. In this review article we have made an attempt to collate the various methods and parameters most frequently used for screening of antiosteoporotic activity in postmenopausal osteoporosis. Pertaining to ovariectomized animal model, this is the most appropriate model for studying the efficacy of different drugs to prevent bone loss in postmenopausal osteoporosis.<\/jats:p>","DOI":"10.1515\/jcim-2015-0034","type":"journal-article","created":{"date-parts":[[2015,7,28]],"date-time":"2015-07-28T03:27:02Z","timestamp":1438054022000},"page":"251-266","source":"Crossref","is-referenced-by-count":15,"title":["Experimental techniques for screening of antiosteoporotic activity in postmenopausal osteoporosis"],"prefix":"10.1515","volume":"12","author":[{"given":"Swaha","family":"Satpathy","sequence":"first","affiliation":[{"name":"Institute of Pharmacy, Guru Ghasidas Vishwavidyalaya, Koni, Bilaspur, Chhattisgarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arjun","family":"Patra","sequence":"additional","affiliation":[{"name":"Institute of Pharmacy, Guru Ghasidas Vishwavidyalaya, Koni, Bilaspur, Chhattisgarh, 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