{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T17:51:43Z","timestamp":1791395503963,"version":"4.3.3"},"reference-count":22,"publisher":"Walter de Gruyter GmbH","issue":"3","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jcim-2026-0231_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Chemotherapy-induced anemia (CIA) is a frequent condition among breast cancer patients who are treated with systemic chemotherapy, and is linked to fatigue, decreased functional capacity, and poor quality of\u00a0life. To determine the prevalence of chemotherapy-induced anaemia and evaluate its impact on the quality of life of breast cancer patients receiving chemotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jcim-2026-0231_abs_003\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross-sectional study was performed at the Ghurki Trust Teaching Hospital in Lahore, Pakistan, from January 2024 to April 2025. The trial included 100 female patients with histopathologically confirmed breast cancer who had received a minimum of three treatment cycles. Anaemia was determined using World Health Organization guidelines (Hb&lt;12\u202fg\/dL), and haemoglobin was assessed using an automated haematology analyser. The quality of life was evaluated via the EORTC QLQ-C30 questionnaire. The data were examined with SPSS version\u00a027.0.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jcim-2026-0231_abs_004\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The average age of participants was 50.7\u00a0\u00b1\u00a010.8 years. Anaemia produced by chemotherapy was seen in 61.0\u202f% of patients, including mild (30.0\u202f%), moderate (24.0\u202f%), and severe (7.0\u202f%) cases. Anaemic patients had a much lower global health status score than non-anaemic patients (54.3\u00a0\u00b1\u00a012.7 vs. 74.8\u00a0\u00b1\u00a010.4, p&lt;0.001). There were significant reductions in physical, emotional, and social functioning ratings, with an elevation in tiredness scores (65.9\u00a0\u00b1\u00a016.1 vs. 37.8\u00a0\u00b1\u00a011.5, p&lt;0.001). Moderate-to-severe anaemia independently forecasted decreased quality of life (OR=3.48, 95\u202f% CI: 1.62\u20137.45, p=0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jcim-2026-0231_abs_005\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patients with breast cancer undergoing chemotherapy often suffer from anaemia, which negatively impacts their quality of life. Appropriate management may improve treatment outcomes early\u00a0on.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jcim-2026-0231","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T14:55:25Z","timestamp":1788188125000},"page":"506-512","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of chemotherapy-induced anemia and its impact on quality of life in breast cancer patients"],"prefix":"10.1515","volume":"23","author":[{"given":"Ramsha","family":"Batool","sequence":"first","affiliation":[{"name":"Ghurki Trust Teaching Hospital , Lahore , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tehreem","family":"Hayat","sequence":"additional","affiliation":[{"name":"Ghurki Trust Teaching Hospital , Lahore , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hira Rizwan","family":"Butt","sequence":"additional","affiliation":[{"name":"Ghurki Trust Teaching Hospital , Lahore , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima Um","family":"Ul Baneen","sequence":"additional","affiliation":[{"name":"Ghurki Trust Teaching Hospital , Lahore , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hooria","family":"Fayyaz","sequence":"additional","affiliation":[{"name":"Department of Surgery , Ghurki Trust Teaching Hospital , Lahore , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tayyaba","family":"Rafiq","sequence":"additional","affiliation":[{"name":"Pak Red Crescent Teaching Hospital , Lahore , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehrulnisa","family":"Akhtar","sequence":"additional","affiliation":[{"name":"Department of Psychology , National University of Modern Languages (NUML) , Islamabad , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uswa","family":"Fayyaz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology , Nishtar Hospital , Multan , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Akhtar Saeed Medical College , Lahore , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayesha","family":"Azeem","sequence":"additional","affiliation":[{"name":"Akhtar Saeed Medical College , Lahore , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mah Gul","family":"Khan","sequence":"additional","affiliation":[{"name":"FMH College of Medicine and Dentistry , Lahore , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahnoor Ikram","family":"Khan","sequence":"additional","affiliation":[{"name":"Fatima Jinnah Medical University , Lahore , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Farooq","sequence":"additional","affiliation":[{"name":"King Edward Medical University , Lahore , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amina","family":"Shahid","sequence":"additional","affiliation":[{"name":"University of Biological and Applied Sciences , Lahore , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2026,9,1]]},"reference":[{"key":"2026100716595863434_j_jcim-2026-0231_ref_001","doi-asserted-by":"crossref","unstructured":"Bekes, I, Eichler, M, Singer, S, Friedl, TWP, Harbeck, N, Rack, B, et al.. 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