{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T05:06:44Z","timestamp":1776056804998,"version":"3.50.1"},"reference-count":8,"publisher":"Walter de Gruyter GmbH","issue":"10","license":[{"start":{"date-parts":[[2022,7,14]],"date-time":"2022-07-14T00:00:00Z","timestamp":1657756800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,9,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A 57-year-old man who had recurrent respiratory infections due to tobacco use and severe chronic obstructive pulmonary disease (COPD) was evaluated as an outpatient to discern the etiology. He was followed with a chest X-ray and a chest computed tomography (CT) scan that displayed a left upper lobe cavitary lung abnormality. The lesion was further evaluated with a CT-guided biopsy, and it was identified as a lung abscess. A tissue culture isolated <jats:italic>Propionibacterium acnes<\/jats:italic>. We present a rare case of\u00a0a common skin commensal, <jats:italic>P.\u00a0acnes<\/jats:italic>, that infected the left upper lobe of the lung. We presume that the patient was\u00a0predisposed to infection secondary to degradation of pulmonary parenchyma by severe bullous emphysema. This destruction created an inflammatory and colonizing space for organisms, even uncommon forms, to flourish. Initially this presentation prompted a differential of pulmonary tuberculosis; however, with further workup, the diagnosis was excluded. This case highlights the potential of <jats:italic>P.\u00a0acnes,<\/jats:italic> an uncommon lung microbe, to lead to a lung abscess in a patient who was otherwise immunocompetent. This case will allow osteopathic clinicians to detect an uncommon microorganism that can potentially cause a pulmonary abscess in a patient with a medical history of severe bullous emphysematous COPD.<\/jats:p>","DOI":"10.1515\/jom-2021-0240","type":"journal-article","created":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T09:13:27Z","timestamp":1657703607000},"page":"493-497","source":"Crossref","is-referenced-by-count":4,"title":["<i>Propionibacterium acnes<\/i>: an uncommon cause of lung abscess in chronic obstructive pulmonary disease complicated with bullous emphysema"],"prefix":"10.1515","volume":"122","author":[{"given":"Arun","family":"Adlakha","sequence":"first","affiliation":[{"name":"Carolina Lung Clinic , Piedmont Medical Center , Rock Hill , SC , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neha","family":"Muppala","sequence":"additional","affiliation":[{"name":"Edward Via College of Medicine-Carolinas , Spartanburg , SC , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2022,7,14]]},"reference":[{"key":"2022092308092343788_j_jom-2021-0240_ref_001","doi-asserted-by":"crossref","unstructured":"Veitch, D, Abioye, A, Morris-Jones, S, McGregor, A. Propionibacterium acnes as a cause of lung abscess in a cardiac transplant recipient. BMJ Case Rep 2015;2015:bcr2015212431. https:\/\/doi.org\/10.1136\/bcr-2015-212431.","DOI":"10.1136\/bcr-2015-212431"},{"key":"2022092308092343788_j_jom-2021-0240_ref_002","doi-asserted-by":"crossref","unstructured":"Achermann, Y, Goldstein, EJ, Coenye, T, Shirtliff, ME. Propionibacterium acnes: from commensal to opportunistic biofilm-associated implant pathogen. Clin Microbiol Rev 2014;27:419\u201340. https:\/\/doi.org\/10.1128\/CMR.00092-13.","DOI":"10.1128\/CMR.00092-13"},{"key":"2022092308092343788_j_jom-2021-0240_ref_003","doi-asserted-by":"crossref","unstructured":"Lawrence, H, Moore, T, Webb, K, Lim, WS. Propionibacterium acnes pleural empyema following medical thoracoscopy. Respirol Case Rep 2017;5:e00249. https:\/\/doi.org\/10.1002\/rcr2.249.","DOI":"10.1002\/rcr2.249"},{"key":"2022092308092343788_j_jom-2021-0240_ref_004","unstructured":"Kuhajda, I, Zarogoulidis, K, Tsirgogianni, K, Tsavlis, D, Kioumis, I, Kosmidis, C, et al.. Lung abscess-etiology, diagnostic and treatment options. Ann Transl Med 2015;3:183. https:\/\/doi.org\/10.3978\/j.issn.2305-5839.2015.07.08."},{"key":"2022092308092343788_j_jom-2021-0240_ref_005","doi-asserted-by":"crossref","unstructured":"de Prost, N, Lavol\u00e9, A, Taillade, L, Wislez, M, Cadranel, J. Gefitinib-associated Propionibacterium acnes pleural empyema. J Thorac Oncol 2008;3:556\u20137. https:\/\/doi.org\/10.1097\/JTO.0b013e31816e2417.","DOI":"10.1097\/JTO.0b013e31816e2417"},{"key":"2022092308092343788_j_jom-2021-0240_ref_006","doi-asserted-by":"crossref","unstructured":"Durand, M, Godbert, B, Anne, V, Grosdidier, G. Large thoracomyoplasty and negative pressure therapy for late postpneumonectomy empyema with a retrosternal abscess: a modern version of the Clagett procedure. Interact Cardiovasc Thorac Surg 2011;12:888\u20139. https:\/\/doi.org\/10.1510\/icvts.2010.262220.","DOI":"10.1510\/icvts.2010.262220"},{"key":"2022092308092343788_j_jom-2021-0240_ref_007","doi-asserted-by":"crossref","unstructured":"Kurz, M, Kaufmann, BA, Baddour, LM, Widmer, AF. Propionibacterium acnes prosthetic valve endocarditis with abscess formation: a case report. BMC Infect Dis 2014;14:105. https:\/\/doi.org\/10.1186\/1471-2334-14-105.","DOI":"10.1186\/1471-2334-14-105"},{"key":"2022092308092343788_j_jom-2021-0240_ref_008","unstructured":"Gekowski, KM, Lopes, R, LiCalzi, L, Bia, FJ. Splenic abscess caused\u00a0by Propionibacterium acnes. Yale J Biol Med 1982;55:65\u20139."}],"container-title":["Journal of Osteopathic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jom-2021-0240\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jom-2021-0240\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T08:10:51Z","timestamp":1663920651000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jom-2021-0240\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,14]]},"references-count":8,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2022,6,17]]},"published-print":{"date-parts":[[2022,9,26]]}},"alternative-id":["10.1515\/jom-2021-0240"],"URL":"https:\/\/doi.org\/10.1515\/jom-2021-0240","relation":{},"ISSN":["2702-3648"],"issn-type":[{"value":"2702-3648","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,14]]}}}