{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T22:48:40Z","timestamp":1776725320348,"version":"3.51.2"},"reference-count":21,"publisher":"Walter de Gruyter GmbH","issue":"4","license":[{"start":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T00:00:00Z","timestamp":1674777600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jom-2022-0127_abs_001\">\n                  <jats:title>Context<\/jats:title>\n                  <jats:p>Lymphatic treatments are gentle and passive techniques believed to enhance movement of lymph back into the central circulatory system. Animal studies provide supportive evidence, yet there are few studies in humans.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jom-2022-0127_abs_002\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The aim of this study is to investigate whether the osteopathic pedal pump protocol reduces volume in the lower limbs of healthy subjects.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jom-2022-0127_abs_003\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A total of 30 first- and second-year medical students were recruited. Subjects were excluded from participating if they had acute asthma, chronic obstructive pulmonary disease (COPD), congestive heart failure, active infections, fractures of the lower extremities, or metastatic cancer. A within-subjects study design with pre- and posttreatment measurement of lower limb volume was utilized. Pretreatment lower limb volume measurements were obtained utilizing a volumetric water gauge prior to\u00a0myofascial thoracic inlet release and\u00a0a 5\u00a0min pedal lymphatic pump protocol treatment. Posttreatment lower limb measurements were taken immediately following the protocol treatment. A telephone interview was conducted 2\u20133\u00a0days after the treatment to assess the participants\u2019 experience of the treatment and whether the treatment elicited a subjective change from baseline. A paired t test was utilized to determine the statistical significance of volume displacement posttreatment.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jom-2022-0127_abs_004\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The mean change of pretreatment to posttreatment lower limb volume was\u00a0\u221245.63\u00a0mL with a standard deviation of 37.65\u00a0mL. The change between the pretreatment and posttreatment volume measurements was statistically significant (p&lt;0.001). The minimum displacement was\u00a0+19\u00a0mL, and the maximum displacement was\u00a0\u2212167\u00a0mL. The majority of participants perceived the treatment as effective and enjoyable, were likely to recommend it to others, and were willing to have it performed on them at routine office visits if there was a need.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jom-2022-0127_abs_005\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The osteopathic pedal pump technique, when utilized on those without leg lymphedema, reduces lower limb volume as measured by the volumetric water gauge. Further studies are warranted, especially in persons with excess lower-extremity edema, lymphedema or venous stasis.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jom-2022-0127","type":"journal-article","created":{"date-parts":[[2023,1,26]],"date-time":"2023-01-26T14:29:58Z","timestamp":1674743398000},"page":"201-206","source":"Crossref","is-referenced-by-count":2,"title":["Does the osteopathic pedal pump reduce lower limb volume in healthy subjects?"],"prefix":"10.1515","volume":"123","author":[{"given":"Jill S.","family":"Adams","sequence":"first","affiliation":[{"name":"Rowan-Virtua School of Osteopathic Medicine , Stratford , NJ , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sahil H.","family":"Parikh","sequence":"additional","affiliation":[{"name":"Rowan-Virtua School of Osteopathic Medicine , Stratford , NJ , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon J.","family":"Goodwin","sequence":"additional","affiliation":[{"name":"Rowan-Virtua School of Osteopathic Medicine , Stratford , NJ , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald R.","family":"Noll","sequence":"additional","affiliation":[{"name":"Department of Geriatrics and Gerontology , Rowan-Virtua School of Osteopathic Medicine, New Jersey Institute for Successful Aging , Stratford , NJ , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2023,1,27]]},"reference":[{"key":"2023032304062522041_j_jom-2022-0127_ref_001","unstructured":"Millard, FP, Walmsley, AG. Applied anatomy of the lymphatics. Kirksville, MO: The Journal printing company; 1922."},{"key":"2023032304062522041_j_jom-2022-0127_ref_002","unstructured":"Miller, CE. Osteopathic treatment of acute infections by means of the lymphatics. J Am Osteopath Assoc 1920;19:494\u20139."},{"key":"2023032304062522041_j_jom-2022-0127_ref_003","unstructured":"Miller, CE. The mechanics of lymphatic circulation: lymph hearts. J\u00a0Am Osteopath Assoc 1923;22:397\u20138. 415\u2013416."},{"key":"2023032304062522041_j_jom-2022-0127_ref_004","unstructured":"Miller, CE. The specific cure of pneumonia. J Am Osteopath Assoc 1927;27:35\u20138."},{"key":"2023032304062522041_j_jom-2022-0127_ref_005","doi-asserted-by":"crossref","unstructured":"Franzini, D, Cuny, LA, Pierce-Talsma, S. Osteopathic lymphatic pump techniques. 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