{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T09:28:28Z","timestamp":1787304508242,"version":"build-2736575974"},"reference-count":20,"publisher":"Walter de Gruyter GmbH","issue":"9","license":[{"start":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:00:00Z","timestamp":1771977600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jom-2024-0183_abs_001\">\n                    <jats:title>Context<\/jats:title>\n                    <jats:p>Acute neck and low back pain are common emergency department (ED) presentations, generally treated with nonsteroidal anti-inflammatory drugs (NSAIDs). Osteopathic manipulative treatment (OMT) is a hands-on treatment modality utilized to treat a variety of musculoskeletal conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jom-2024-0183_abs_002\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We sought to evaluate the relative efficacies and side effects of hands-on OMT vs. one dose of oral ibuprofen, in the treatment of adult patients presenting with acute neck or back\u00a0pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jom-2024-0183_abs_003\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a prospective randomized controlled trial at a high-volume urban ED. Adult patients with acute neck or low back pain were randomized to 5\u202fmin of OMT or oral ibuprofen 400\u202fmg. Primary endpoint was the reduction in pain. Secondary outcomes included patient satisfaction and the rate of adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jom-2024-0183_abs_004\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty-eight patients were enrolled; 35 were included in the final analysis. Twenty patients were randomized to OMT, 15 to ibuprofen. Median pain reduction on the Numeric Rating Scale 11 (NRS-11) scale was 2.0 points for OMT and 1.0 point for ibuprofen (p=0.11) at 30\u202fmin; 2.5 points for OMT and 2.0 points for ibuprofen (p=0.22) at 60\u202fmin. There was no significant difference between groups. Nor were there any significant differences on the 5-point Pain Relief Scale (PRS-5) scale (p=0.36), or in any of the secondary outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jom-2024-0183_abs_005\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this small, unblinded, single-center randomized trial, we found no significant difference in utilizing OMT compared to 400\u202fmg of oral ibuprofen for patients with acute neck or low back pain, regarding pain control, patient satisfaction, or side effects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jom-2024-0183","type":"journal-article","created":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T14:34:18Z","timestamp":1772289258000},"page":"431-438","source":"Crossref","is-referenced-by-count":1,"title":["Osteopathic manipulative treatment vs. standard therapy in the management of acute neck and low back pain in the emergency department"],"prefix":"10.1515","volume":"126","author":[{"given":"Steven M.","family":"Hochman","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine , 6473 St. Joseph\u2019s Health , Paterson , NJ , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Vlasica","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine , 6473 St. Joseph\u2019s Health , Paterson , NJ , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"LaPietra","sequence":"additional","affiliation":[{"name":"Emergency Medicine Service Line, Robert Wood Johnson\u00a0\u2013\u00a0Barnabas Health , West Orange , NJ , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhargavi K.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine , 6473 St. Joseph\u2019s Health , Paterson , NJ , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Ju","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine , Houston, University of Texas Health Science Center at Houston , Houston , TX , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas J.","family":"Mota","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine , Memorial Hospital, Maine Health , Portland , ME , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Wilder","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine , Kaiser Permanente , Modesto , CA , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2026,2,25]]},"reference":[{"key":"2026082109152254864_j_jom-2024-0183_ref_001","unstructured":"United States Bone and Joint, Initiative. 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