{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T13:31:25Z","timestamp":1794317485646,"version":"4.9.0"},"reference-count":0,"publisher":"Walter de Gruyter GmbH","issue":"s2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,12,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p> Type 2 diabetes mellitus (DM) has been considered rare in the pediatric population. However, over the last decade, there has been a disturbing upswing in the rate of diagnosis of type 2 DM in the pediatric age group, mirroring the increasing rates of obesity in childhood. The pathophysiology of type 2 DM discussed in this article focuses on the delicate balance between insulin sensitivity and insulin secretion. The risk factors for youth-onset type 2 DM are presented, with careful evaluation of their impact on insulin sensitivity versus insulin secretion.<\/jats:p>","DOI":"10.1515\/jpem-2000-s612","type":"journal-article","created":{"date-parts":[[2014,7,23]],"date-time":"2014-07-23T12:25:04Z","timestamp":1406118304000},"page":"1385-1394","source":"Crossref","is-referenced-by-count":74,"title":["Type 2 Diabetes Mellitus in Children: Pathophysiology and Risk Factors"],"prefix":"10.1515","volume":"13","author":[{"given":"Silva A.","family":"Arslanian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2014,7,22]]},"container-title":["Journal of Pediatric Endocrinology and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpem-2000-s612\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpem-2000-s612\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,10]],"date-time":"2021-10-10T18:47:02Z","timestamp":1633891622000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpem-2000-s612\/html"}},"subtitle":["Division of Pediatric Endocrinology, Metabolism and Diabetes Mellitus Children\u2019s Hospital of Pittsburgh, Pennsylvania, USA"],"short-title":[],"issued":{"date-parts":[[2000,12,1]]},"references-count":0,"journal-issue":{"issue":"s2","published-online":{"date-parts":[[2014,7,22]]},"published-print":{"date-parts":[[2000,12,1]]}},"alternative-id":["10.1515\/jpem-2000-s612"],"URL":"https:\/\/doi.org\/10.1515\/jpem-2000-s612","relation":{},"ISSN":["2191-0251","0334-018X"],"issn-type":[{"value":"2191-0251","type":"electronic"},{"value":"0334-018X","type":"print"}],"subject":[],"published":{"date-parts":[[2000,12,1]]}}}