{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:03:20Z","timestamp":1760781800835},"reference-count":34,"publisher":"Walter de Gruyter GmbH","issue":"7-8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report two newborns with female external genitalia and bilateral inguinal swelling who were diagnosed with 17\u03b2-hydroxysteroid dehydrogenase type 3 deficiency, a rare cause of 46,XY disorder of sexual development. The first case had normal clitoral size and vaginal and urethral openings, palpable gonads in the inguinal region, low testosterone, and low levels of basal and GNRH-stimulated gonadotropin. The second case had similar external genitalia, low testosterone but borderline basal and normal stimulated gonadotropin levels. Low testosterone\/androstenedione ratios (0.22 and 0.24, respectively; normal, &gt;0.8) after human chorionic gonadotropin stimulation indicated 17\u03b2-hydroxysteroid dehydrogenase type 3 deficiency.<\/jats:p>","DOI":"10.1515\/jpem-2014-0365","type":"journal-article","created":{"date-parts":[[2015,4,16]],"date-time":"2015-04-16T13:35:05Z","timestamp":1429191305000},"source":"Crossref","is-referenced-by-count":4,"title":["Two different patterns of mini-puberty in two 46,XY newborns with 17\u03b2-hydroxysteroid dehydrogenase type 3 deficiency"],"prefix":"10.1515","volume":"28","author":[{"given":"Korcan","family":"Demir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melek","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zlem Nalbanto\u011flu","family":"Elmas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00fcseyin An\u0131l","family":"Korkmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selma","family":"Tun\u00e7","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zg\u00fcr","family":"Olukman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filiz","family":"Hazan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keramettin U\u011fur","family":"\u00d6zkan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Behzat","family":"\u00d6zkan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref211","first-page":"53","article-title":"AS The testosterone androstenedione ratio in male undermasculinization","author":"Faisal","year":"2000","journal-title":"Clin Endocrinol"},{"key":"ref161","first-page":"455","article-title":"beta - 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hydroxysteroid dehydrogenase type gene associated with male pseudohermaphroditism","volume":"17","author":"Bilbao","year":"1998","journal-title":"Eur J Endocrinol"},{"key":"ref291","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1007\/BF03345738","article-title":"beta - hydroxysteroid dehydrogenase deficiency From pregnancy to adolescence","volume":"17","author":"Bertelloni","year":"2009","journal-title":"J Endocrinol Invest"},{"key":"ref231","first-page":"127","article-title":"Normal ranges for immunochemiluminometric gonadotropin assays","volume":"40","author":"Neely","year":"1995","journal-title":"J Pediatr"},{"key":"ref121","first-page":"112","article-title":"el Male pseudohermaphroditism due to \u03b2 - hydroxysteroid dehydrogenase deficiency : gender reassignment in early infancy","volume":"17","author":"Gross","year":"1986","journal-title":"Acta Endocrinol"},{"key":"ref241","first-page":"95","article-title":"novel ultrapressure liquid chromatography tandem mass spectrometry method for the simultaneous determination of androstenedione testosterone and dihydrotestosterone in pediatric blood samples : age - 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