{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T05:44:57Z","timestamp":1767851097456,"version":"3.49.0"},"reference-count":28,"publisher":"Walter de Gruyter GmbH","issue":"7-8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Gonadotropin-releasing hormone analogues are used in the treatment of prostate cancer, breast cancer, endometriosis, and uterine leiomyomas in adults and often in the treatment of precocious puberty in children. Many adverse effects have been reported for gonadotropin-releasing hormone analogues, but anaphylaxis is rarely reported as an adverse effect. Frequent cross-reactions, particularly during childhood, and diversity of the time of onset of anaphylactic manifestations complicate the diagnosis. A patient who exhibited anaphylactic allergic reactions to two different agents used in the treatment of central precocious puberty presented here because the case has an atypical course and is the first in the literature.<\/jats:p>","DOI":"10.1515\/jpem-2014-0402","type":"journal-article","created":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T17:23:26Z","timestamp":1424712206000},"source":"Crossref","is-referenced-by-count":6,"title":["A patient developing anaphylaxis and sensitivity to two different GnRH analogues and a review of literature"],"prefix":"10.1515","volume":"28","author":[{"given":"Deniz","family":"\u00d6kdemir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nihal","family":"Hatipo\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Himmet Haluk","family":"Akar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00dclk\u00fc","family":"G\u00fcl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leyla","family":"Ak\u0131n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fulya","family":"Tahan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selim","family":"Kurto\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref141","first-page":"284","article-title":"Anaphylaxis to leuprolide acetate depot injection during treatment for prostate cancer","volume":"5","author":"Grant","year":"2007","journal-title":"Clin Cancer"},{"key":"ref101","first-page":"210","article-title":"Verlag","author":"Braun","year":"1991","journal-title":"Dermatology"},{"key":"ref251","first-page":"210","article-title":"Verlag","author":"Braun","year":"1991","journal-title":"Dermatology"},{"key":"ref121","first-page":"312","article-title":"Case report systemic hypersensitivity reaction to goserelin acetate","author":"Karadsheh","year":"1996","journal-title":"Am J Med Sci"},{"key":"ref71","first-page":"16","article-title":"Emergency treatment of anaphylaxis in infants and children","author":"Cheng","year":"2011","journal-title":"Paediatr Health"},{"key":"ref191","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s00774-005-0618-3","article-title":"Long - 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