{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T17:19:41Z","timestamp":1763140781055},"reference-count":18,"publisher":"Walter de Gruyter GmbH","issue":"11-12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Association of Kocher-Debr\u00e9-Semelaigne syndrome\u2013a myopathy of hypothyroidism in childhood characterized by muscular hypertrophy, with rhabdomyolysis is very rare. We present a case of Kocher-Debr\u00e9-Semelaigne syndrome with rhabdomyolysis secondary to Hashimoto\u2019s thyroiditis. He had muscular symptoms simulating poly\/dermatomyositis, massively elevated creatine kinase (CK) levels and high creatinine levels. All of the findings reversed on treatment of hypothyroidism. The response to the therapy strongly suggested that Kocher-Debr\u00e9-Semelaigne (KDS) syndrome was the underlying etiology. Serum thyroid- stimulating hormone levels should be routinely determined in all patients with muscular symptoms and\/or elevation of CK and creatinine, keeping KDS syndrome in mind.<\/jats:p>","DOI":"10.1515\/jpem-2014-0411","type":"journal-article","created":{"date-parts":[[2015,7,16]],"date-time":"2015-07-16T17:10:02Z","timestamp":1437066602000},"source":"Crossref","is-referenced-by-count":5,"title":["Kocher-Debr\u00e9-Semelaigne syndrome with rhabdomyolysis and increased creatinine"],"prefix":"10.1515","volume":"28","author":[{"given":"Emine Ay\u00e7a","family":"Cimbek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya\u015far","family":"\u015een","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sevil Ar\u0131","family":"Yuca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demet","family":"\u00c7am","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celal","family":"G\u00fcr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harun","family":"Peru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref121","first-page":"128","article-title":"syndrome a rare case report with orofacial manifestations","volume":"28","author":"Panat","year":"2013","journal-title":"Med"},{"key":"ref51","article-title":"Semelaigne syndrome with arrhythmogenic right ventricular cardiomyopathy : a hitherto unrecognized association","volume":"16","author":"Moorthy","year":"2012","journal-title":"J Endocrinol Metab"},{"key":"ref61","first-page":"3","article-title":"Report of two cases of Kocher syndrome","volume":"25","author":"Uzun","year":"2005"},{"key":"ref141","first-page":"13","article-title":"Semelaigne syndrome a case eport People","author":"Kapoor","year":"2009","journal-title":"Sci Res"},{"key":"ref21","first-page":"128","article-title":"syndrome a rare case report with orofacial manifestations","volume":"28","author":"Panat","year":"2013","journal-title":"Med"},{"key":"ref41","first-page":"13","article-title":"Semelaigne syndrome a case eport People","author":"Kapoor","year":"2009","journal-title":"Sci Res"},{"key":"ref151","article-title":"Semelaigne syndrome with arrhythmogenic right ventricular cardiomyopathy : a hitherto unrecognized association","volume":"16","author":"Moorthy","year":"2012","journal-title":"J Endocrinol Metab"},{"key":"ref11","article-title":"syndrome Case bcr","author":"Agrawal","year":"2010","journal-title":"Rep"},{"key":"ref71","first-page":"381","article-title":"thyroiditis In editors Kronenberg textbook of th ed 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