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A significant difference in plasma homocysteine concentrations within the normal levels (p=0.032, \u03c7<\/jats:p><jats:p>We have proven that adult patients with PKU and HPA are at risk of vitamin B<\/jats:p>","DOI":"10.1515\/jpem-2014-0489","type":"journal-article","created":{"date-parts":[[2015,7,30]],"date-time":"2015-07-30T17:21:27Z","timestamp":1438276887000},"source":"Crossref","is-referenced-by-count":4,"title":["Long-term treatment for hyperphenylalaninemia and phenylketonuria: a risk for nutritional vitamin B12 deficiency?"],"prefix":"10.1515","volume":"28","author":[{"given":"Dagmar","family":"Proch\u00e1zkov\u00e1","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji\u0159\u00ed","family":"Jarkovsk\u00fd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zdena","family":"Ha\u0148kov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Kone\u010dn\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana","family":"Ben\u00e1kov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana","family":"Vinohradsk\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alena","family":"Miku\u0161kov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","reference":[{"key":"ref541","article-title":"deficiency phenylketonuria","volume":"52","author":"Walter","year":"2011","journal-title":"Vitamin Mol Genet Metab"},{"key":"ref761","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1097\/00005176-199302000-00008","article-title":"Plasma amino acid response to ingestion of amino acids and whole protein","volume":"16","author":"Gropper","year":"1993","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"ref251","first-page":"419","article-title":"Hyperphenylalaninemia in the Republic genotype phenotype correlations and in silico analysis of novel missense mutations","author":"Reblov\u00e1","year":"2013","journal-title":"Clin Chim Acta"},{"key":"ref851","first-page":"83","article-title":"High dietary folic acid and high plasma folate in children and adults with phenylketonuria Reports","volume":"13","author":"Stolen","year":"2013"},{"key":"ref521","first-page":"342","article-title":"deficiency in adolescents and young adults with phenylketonuria","author":"Hanley","year":"1993","journal-title":"Vitamin Lancet"},{"key":"ref481","first-page":"154","article-title":"Controlled diet in phenylketonuria and hyperfenylalaninemia may cause serum selenium deficiency in adult patients the experience Trace Element","author":"Proch\u00e1zkov\u00e1","year":"2013","journal-title":"Biol Res"},{"key":"ref331","doi-asserted-by":"crossref","DOI":"10.1038\/sj.ejcn.1601463","article-title":"AD AH EM amino acid sensing by the calcium - 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