{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T05:30:48Z","timestamp":1688967048201},"reference-count":42,"publisher":"Walter de Gruyter GmbH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,3,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpem-2016-0137_s_999_w2aab3b7b5b1b6b1aab1c16b1Aa\">\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The prevalence of both vitamin D (VitD) deficiency and type 1 diabetes mellitus (T1DM) has increased worldwide over the last few decades. The objectives of this study were: (1) to evaluate the prevalence of VitD deficiency and insufficiency among Israeli youth with T1DM and (2) to assess the association between VitD status, seasonality and T1D glycemic control characteristics.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2016-0137_s_998_w2aab3b7b5b1b6b1aab1c16b2Aa\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This was a multi-centered, cross-sectional study. VitD levels were routinely tested during the years 2008\u20132011 in T1DM patients aged up to 21 years. Medical records were reviewed for demographic, clinical and laboratory characteristics.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2016-0137_s_997_w2aab3b7b5b1b6b1aab1c16b3Aa\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The study population consisted of 199 participants (53% males), mean age 12.24\u00b14.11 years, mean T1DM duration 3.77\u00b13.43 years. VitD levels were within the normal range in 19.6%, insufficient (15\u201329 ng\/mL, 37\u201372 nmol\/L) in 62.3% and deficient (&lt;15 ng\/mL, &lt;37 nmol\/L) in 18.1%. Mean VitD level was higher during the summer than during spring, autumn and winter (28.65 ng\/mL, 23.16 ng\/mL, 21.65 ng\/mL, 17.55 ng\/mL, respectively, p&lt;0.001). Mean VitD level was higher among secular patients compared to the religious (whole-year heavily dressed) population (23.57 ng\/mL, 15.54 ng\/mL, respectively, p&lt;0.001). VitD level was negatively associated with body mass index calculation of standard deviation scores (BMI-SDS), high-density lipoprotein (HDL) and age at diagnosis (r=\u22120.171, p=0.016; r=\u22120.149, p=0.043; r=\u22120.150, p=0.037, respectively). No association was demonstrated with disease duration and glycemic control indices and metabolic parameters.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2016-0137_s_996_w2aab3b7b5b1b6b1aab1c16b4Aa\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>VitD insufficiency is largely prevalent among Israeli youth with T1DM, as is in Israeli youth in general. The VitD level is associated with seasonality, clothing habits and BMI.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpem-2016-0137","type":"journal-article","created":{"date-parts":[[2016,10,19]],"date-time":"2016-10-19T10:02:12Z","timestamp":1476871332000},"page":"323-330","source":"Crossref","is-referenced-by-count":3,"title":["Vitamin D status in Israeli pediatric type 1 diabetes patients: the AWeSoMe Study Group experience and literature review"],"prefix":"10.1515","volume":"33","author":[{"given":"Judith","family":"Brody","sequence":"first","affiliation":[{"name":"Sackler School of Medicine , Tel Aviv University , Tel Aviv , Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orit","family":"Pinhas-Hamiel","sequence":"additional","affiliation":[{"name":"Sackler School of Medicine , Tel Aviv University , Tel Aviv , Israel"},{"name":"Pediatric Endocrine and Diabetes Unit , Safra Children\u2019s Hospital, Sheba Medical Center , Tel-Hashomer , Israel"},{"name":"Juvenile Diabetes Center , Maccabi Health Care Services , Raanana , Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zohar","family":"Landau","sequence":"additional","affiliation":[{"name":"Sackler School of Medicine , Tel Aviv University , Tel Aviv , Israel"},{"name":"Juvenile Diabetes Center , Maccabi Health Care Services , Raanana , Israel"},{"name":"Pediatric Diabetes Service , Wolfson Medical Center , Holon , Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adi","family":"Adar","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology Service, Division of Pediatrics, Assaf Harofeh Medical Center, Sackler School of Medicine , Tel Aviv University , Zerifin , Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tzvy","family":"Bistritzer","sequence":"additional","affiliation":[{"name":"Sackler School of Medicine , Tel Aviv University , Tel Aviv , Israel"},{"name":"Pediatric Endocrinology Service, Division of Pediatrics, Assaf Harofeh Medical Center, Sackler School of Medicine , Tel Aviv University , Zerifin , Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianna","family":"Rachmiel","sequence":"additional","affiliation":[{"name":"Pediatric endocrinology and Diabetes Unit , Assaf Harofeh Medical Center , Zerifin 70300 , Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2016,10,19]]},"reference":[{"key":"2023040101053371191_j_jpem-2016-0137_ref_001_w2aab3b7b5b1b6b1ab2b2b1Aa","doi-asserted-by":"crossref","unstructured":"Bikle D. 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