{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T01:26:12Z","timestamp":1774488372118,"version":"3.50.1"},"reference-count":16,"publisher":"Walter de Gruyter GmbH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background:<\/jats:title><jats:p>To what extent high sensitivity C-reactive protein (hsCRP) is associated with known cardiovascular risk factors in children with type 1 diabetes (T1D) has not been fully explored.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Forty-two T1D children (age: 12+\/\u22121 years) without hypertension, retinopathy, hypothyroidism, albuminuria or other endocrine diseases and 20 controls were studied. Out of the 42 T1D patients studied 57% were prepubertal or early pubertal (Tanner I\/II), 38% were pubertal (Tanner III\/IV) and 5% post-pubertal (Tanner V).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Children with T1D showed higher hsCRP than controls [0.51 (0.31\u20131.71 vs. 0.20 (0.20\u20130.90) mg\/L, p&lt;0.05]. However, hsCRP levels were not different in subgroup analysis [hemoglobin A<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Non-HDL-cholesterol might be more useful than hsCRP to evaluate future cardiovascular risk in children with T1D.<\/jats:p><\/jats:sec>","DOI":"10.1515\/jpem-2016-0307","type":"journal-article","created":{"date-parts":[[2017,2,21]],"date-time":"2017-02-21T14:25:24Z","timestamp":1487687124000},"source":"Crossref","is-referenced-by-count":10,"title":["Non-HDL-cholesterol and C-reactive protein in children and adolescents with type 1 diabetes"],"prefix":"10.1515","volume":"30","author":[{"given":"Mar\u00eda Mercedes","family":"Prado","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresita","family":"Carrizo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adela Victoria","family":"Abreg\u00fa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom\u00e1s","family":"Mero\u00f1o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref61","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1194\/jlr.P060657","article-title":"Associations between intensive diabetes therapy and NMR-determined lipoprotein subclass profiles in type 1 diabetes","volume":"57","year":"2016","journal-title":"J Lipid Res"},{"key":"ref121","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1007\/s00246-006-1199-1","article-title":"Evidence for an association between type 1 diabetes and premature carotid atherosclerosis in childhood","volume":"27","year":"2006","journal-title":"Pediatr Cardiol"},{"key":"ref151","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1161\/01.ATV.0000228818.11968.7a","article-title":"Childhood C-reactive protein in predicting CRP and carotid intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns Study","volume":"26","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1016\/S0140-6736(09)60568-7","article-title":"Incidence trends for childhood type 1 diabetes in Europe during 1989\u20132003 and predicted new cases 2005\u201320: a multicentre prospective registration study","volume":"373","year":"2009","journal-title":"Lancet"},{"key":"ref01","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1016\/S0140-6736(09)60568-7","article-title":"Incidence trends for childhood type 1 diabetes in Europe during 1989\u20132003 and predicted new cases 2005\u201320: a multicentre prospective registration 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