{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T03:44:12Z","timestamp":1775447052863,"version":"3.50.1"},"reference-count":32,"publisher":"Walter de Gruyter GmbH","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,1,1]]},"abstract":"<jats:title>Abstract:<\/jats:title><jats:sec><jats:title>Background:<\/jats:title><jats:p>The majority of children who present for evaluation of tall stature fall under the diagnosis of constitutional tall stature (CTS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>To investigate mechanisms of tall stature, we evaluated serum IGF-I values and the expression of the<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Our results showed significantly lower IGF-I levels in children with short stature (\u22120.57\u00b10.18 SDS) compared to control children (0.056\u00b10.19 SDS; p&lt;0.0001) and to subjects with tall stature (0.594\u00b10.17; p=0.00067). Furthermore, we found significantly higher<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Significantly higher<\/jats:p><\/jats:sec>","DOI":"10.1515\/jpem-2016-0355","type":"journal-article","created":{"date-parts":[[2017,3,16]],"date-time":"2017-03-16T15:33:04Z","timestamp":1489678384000},"source":"Crossref","is-referenced-by-count":13,"title":["Analysis of growth hormone receptor gene expression in tall and short stature children"],"prefix":"10.1515","volume":"30","author":[{"given":"Sara","family":"Pagani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Radetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Meazza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Bozzola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref251","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1007\/s00439-013-1394-0","article-title":"Common DNA variants predict tall stature in Europeans","volume":"133","year":"2014","journal-title":"Hum Genet"},{"key":"ref171","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1177\/014616728063010","article-title":"The male taller norm in mate 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