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Androgen receptor (<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Two patients were found with<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Short term and local application of DHT at low doses in patients with micropenis could accelerate penile growth effectively without evident side effects; however, precautions still need be taken due to the paucity of long term study and the lack of ideal DHT dosage.<\/jats:p><\/jats:sec>","DOI":"10.1515\/jpem-2016-0400","type":"journal-article","created":{"date-parts":[[2017,11,25]],"date-time":"2017-11-25T22:16:19Z","timestamp":1511648179000},"source":"Crossref","is-referenced-by-count":20,"title":["Efficacy and safety of percutaneous administration of dihydrotestosterone in children of different genetic backgrounds with micropenis"],"prefix":"10.1515","volume":"30","author":[{"given":"Dan","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangsheng","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Xi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruoqian","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhou","family":"Pei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunli","family":"Bi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuangsui","family":"Ruan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feihong","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","reference":[{"key":"ref301","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.jpeds.2006.07.044","article-title":"Bilateral anorchia in infancy: occurence of micropenis and the effect of testosterone treatment","volume":"149","year":"2006","journal-title":"J Pediatr"},{"key":"ref121","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1111\/j.1464-410X.2008.08240.x","article-title":"Prostate-specific antigen changes and prostate cancer in hypogonadal men treatment with testosterone replacement therapy","volume":"103","year":"2009","journal-title":"BJU Int"},{"key":"ref101","first-page":"432","article-title":"Normal penile growth amongst Chinese","volume":"31","year":"2010","journal-title":"Chin J Pediatr Surg"},{"key":"ref281","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.pedhc.2009.05.001","article-title":"When size matters: a clinical review of pathological micropenis","volume":"24","year":"2010","journal-title":"J Pediatr Health Care"},{"key":"ref201","first-page":"15018232","article-title":"Correlation of androgen receptor and SRD5A2 gene mutations with pediatric hypospadias in 46, XY DSD children","volume":"15","year":"2016","journal-title":"Genet Mol Res"},{"key":"ref261","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/S0022-5347(01)67175-1","article-title":"Micropenis: does early treatment with testosterone do more harm than good?","volume":"154","year":"1995","journal-title":"J Urol"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1111\/j.1439-0272.2007.00786.x","article-title":"Safety aspects of androgen treatment with 5 alpha-dihydrotestosterone","volume":"39","year":"2007","journal-title":"Andrologia"},{"key":"ref311","first-page":"156","article-title":"Micropenis. 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