{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T10:59:04Z","timestamp":1771671544521,"version":"3.50.1"},"reference-count":26,"publisher":"Walter de Gruyter GmbH","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,1,28]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background:<\/jats:title><jats:p>Hyperparathyroidism (HPT) is a rare disease in the pediatric population, and optimal management may be unclear if it is due to an occult parathyroid adenoma. We present a case report of a pediatric patient with an occult, ectopic, supernumerary, parathyroid adenoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation:<\/jats:title><jats:p>A 13-year-old female who initially presented with anxiety was diagnosed with HPT. Preoperative imaging and bilateral neck exploration with four-gland biopsy were negative for any parathyroid adenoma. Postoperative MRI identified a thymic mass. She subsequently underwent video-assisted thoracoscopic thymectomy with resection of an intrathymic parathyroid adenoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>The diagnosis of pediatric HPT is increasing. Supernumerary or occult parathyroid adenomas are rare and add complexity to presurgical planning and management. Our case represents the rare occurrence of a pediatric ectopic supernumerary occult parathyroid adenoma treated with a two-stage approach utilizing multiple imaging studies. We provide a review of the pathology and propose an algorithmic approach to manage these complex patients.<\/jats:p><\/jats:sec>","DOI":"10.1515\/jpem-2017-0077","type":"journal-article","created":{"date-parts":[[2017,8,15]],"date-time":"2017-08-15T10:01:01Z","timestamp":1502791261000},"source":"Crossref","is-referenced-by-count":7,"title":["An occult ectopic parathyroid adenoma in a pediatric patient: a case report and management algorithm"],"prefix":"10.1515","volume":"30","author":[{"given":"Brent D.","family":"Bauman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Evasovich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Louiselle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugene","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Goodwin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miroslav","family":"Sekulic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faqian","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raphael","family":"Andrade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley 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hyperparathyroidism in a paediatric hospital","volume":"89","year":"1996","journal-title":"Q J Med"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1542\/peds.2004-0804","article-title":"Primary hyperparathyroidism in pediatric patients","volume":"115","year":"2005","journal-title":"Pediatrics"},{"key":"ref221","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.jpedsurg.2016.01.018","article-title":"Outcomes of minimally invasive parathyroidectomy in pediatric patients with primary hyperparathyroidism owing to parathyroid adenoma: a single institution experience","volume":"52","year":"2017","journal-title":"J Pediatr Surg"},{"key":"ref141","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1542\/peds.2004-0804","article-title":"Primary hyperparathyroidism in pediatric patients","volume":"115","year":"2005","journal-title":"Pediatrics"},{"key":"ref201","first-page":"157","article-title":"4D Ct \u2013 a diagnostic tool to localize an occult parathyroid adenoma in a patient with primary hyperparathyroidism","volume":"95","year":"2012","journal-title":"Med Health R I"},{"key":"ref251","first-page":"158","article-title":"Intraoperative parathyroid hormone monitoring corroborates the success of parathyroidectomy in children","volume":"6","year":"2014","journal-title":"J Clin Res Pediatr Endocrinol"},{"key":"ref01","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/j.jpedsurg.2010.02.074","article-title":"What is the optimal treatment for children with primary hyperparathyroidism?","volume":"45","year":"2010","journal-title":"J Pediatr Surg"},{"key":"ref71","first-page":"157","article-title":"4D Ct \u2013 a diagnostic tool to localize an occult parathyroid adenoma in a patient with primary hyperparathyroidism","volume":"95","year":"2012","journal-title":"Med Health R I"},{"key":"ref101","first-page":"527","article-title":"Video assisted thoracoscopic excision of mediastinal ectopic parathyroid adenomas: a UK regional experience","volume":"4","year":"2015","journal-title":"Ann Cardiothorac Surg"},{"key":"ref231","first-page":"527","article-title":"Video assisted thoracoscopic excision of mediastinal ectopic parathyroid adenomas: a UK regional experience","volume":"4","year":"2015","journal-title":"Ann Cardiothorac Surg"},{"key":"ref151","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.amjsurg.2016.03.019","article-title":"The changing pattern of diagnosing primary hyperparathyroidism in young patients","volume":"213","year":"2017","journal-title":"Am J Surg"},{"key":"ref131","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/j.jpedsurg.2010.02.074","article-title":"What is the optimal treatment for children with primary hyperparathyroidism?","volume":"45","year":"2010","journal-title":"J Pediatr Surg"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.ijporl.2012.12.008","article-title":"Characterization of hyperparathyroidism in youth and adolescents: a literature review","volume":"77","year":"2013","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.amjsurg.2005.10.049","article-title":"Incidence and location of ectopic abnormal parathyroid glands","volume":"191","year":"2006","journal-title":"Am J Surg"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.amjsurg.2016.03.019","article-title":"The changing pattern of diagnosing primary hyperparathyroidism in young patients","volume":"213","year":"2017","journal-title":"Am J Surg"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"144","DOI":"10.14310\/horm.2002.1231","article-title":"Supernumerary ectopic parathyroid glands. Persistent hyperparathyroidism due to mediastinal parathyroid adenoma localized by preoperative single photon emission computed tomography and intraoperative gamma probe application","volume":"8","year":"2009","journal-title":"Hormones"},{"key":"ref51","first-page":"102","article-title":"Incidence and localization of ectopic parathyroid adenomas in previously unexplored patients","volume":"37","year":"2012","journal-title":"World J Surg"},{"key":"ref191","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.amjsurg.2005.10.049","article-title":"Incidence and location of ectopic abnormal parathyroid glands","volume":"191","year":"2006","journal-title":"Am J Surg"},{"key":"ref211","doi-asserted-by":"crossref","first-page":"144","DOI":"10.14310\/horm.2002.1231","article-title":"Supernumerary ectopic parathyroid glands. 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