{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:09:41Z","timestamp":1787022581863,"version":"build-2736575974"},"reference-count":70,"publisher":"Walter de Gruyter GmbH","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,1,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Fetal goitrous hypothyroidism is mainly caused by maternal treatment of Graves\u2019 disease. Fetal goiter sometimes compresses the trachea and esophagus and may cause polyhydramnios, preterm labor, complications of labor and delivery, and neonatal respiratory disorder.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>We report a case of fetal goitrous hypothyroidism in which the mother had Graves\u2019 disease, which was treated with propylthiouracil. Intra-amniotic levothyroxine (L-T<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Previous reports on fetal goitrous hypothyroidism that was treated with intra-amniotic L-T<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jpem-2017-0094","type":"journal-article","created":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T06:01:40Z","timestamp":1501740100000},"source":"Crossref","is-referenced-by-count":12,"title":["Fetal goitrous hypothyroidism treated by intra-amniotic levothyroxine administration: case report and review of the literature"],"prefix":"10.1515","volume":"30","author":[{"given":"Mami","family":"Kobayashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Yagasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiro","family":"Saito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Nemoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Naito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanji","family":"Sugita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","reference":[{"key":"ref391","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/S0022-3476(05)83178-6","article-title":"Motor and cognitive 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Ther"},{"key":"ref521","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1507\/endocrj.K07-047","article-title":"Successful intrauterine therapy for fetal goitrous hypothyroidism during late gestation","volume":"54","year":"2007","journal-title":"Endocr J"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.3109\/14767058.2014.983062","article-title":"Antenatal diagnosis and treatment of hypothyroid fetal goiter in an euthyroid mother: a case report and review of literature","volume":"28","year":"2015","journal-title":"J Matern Fetal Neonatal Med"},{"key":"ref221","doi-asserted-by":"crossref","first-page":"6093","DOI":"10.1210\/jc.2004-2555","article-title":"Management of Graves\u2019 disease during pregnancy: the key role of fetal thyroid gland monitoring","volume":"90","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"ref241","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1089\/thy.1999.9.1111","article-title":"Resolution of 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J"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1093\/jpepsy\/17.2.187","article-title":"Neurodevelopment in infants and preschool children with congenital hypothyroidism: etiological and treatment factors affecting outcome","volume":"17","year":"1992","journal-title":"J Pediatr Psychol"},{"key":"ref191","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1002\/jcu.20717","article-title":"Intrauterine diagnosis and management of fetal goiter: a case report","volume":"38","year":"2010","journal-title":"J Clin Ultrasound"},{"key":"ref81","first-page":"543","article-title":"Successful in utero treatment of fetal goiter and hypothyroidism","volume":"21","year":"1991","journal-title":"N Engl J Med"},{"key":"ref181","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1159\/000111593","article-title":"Fetal goiter and bilateral ovarian cysts","volume":"23","year":"2008","journal-title":"Fetal Diagn 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