{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T17:28:00Z","timestamp":1783963680262,"version":"3.55.0"},"reference-count":11,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,5,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpem-2017-0463_s_999_w2aab3b7c29b1b6b1aab1c15b1Aa\">\n                  <jats:title>Background:<\/jats:title>\n                  <jats:p>The diagnostic cutoff points for indicators of type 2 diabetes mellitus (T2DM) in the pediatric population have not been defined thus far.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2017-0463_s_998_w2aab3b7c29b1b6b1aab1c15b2Aa\">\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>A retrospective, single-center study was conducted from April 2003 to May 2016. We enrolled 236 overweight or obese children and adolescents aged 4\u201317 years. Thirty-nine (26.9%) of 145 patients had T2DM according to the oral glucose tolerance test results.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2017-0463_s_997_w2aab3b7c29b1b6b1aab1c15b3Aa\">\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>A glycated hemoglobin (HbA<jats:sub>1c<\/jats:sub>) level of 6.5% had a sensitivity and specificity of 87.2% and 98.5%, respectively, for detecting T2DM. The optimal HbA<jats:sub>1c<\/jats:sub> cutoff level for T2DM was &gt;6.2% (94.7% sensitivity, 95.5% specificity).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2017-0463_s_996_w2aab3b7c29b1b6b1aab1c15b4Aa\">\n                  <jats:title>Conclusions:<\/jats:title>\n                  <jats:p>We observed that the use of an HbA<jats:sub>1c<\/jats:sub> level of 6.5% had a lower sensitivity for detecting T2DM than an HbA<jats:sub>1c<\/jats:sub> level of &gt;6.2%.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpem-2017-0463","type":"journal-article","created":{"date-parts":[[2018,4,13]],"date-time":"2018-04-13T22:15:26Z","timestamp":1523657726000},"page":"503-506","source":"Crossref","is-referenced-by-count":6,"title":["Glycated hemoglobin A<sub>1c<\/sub> as a screening test for detecting type 2 diabetes mellitus in obese children and adolescents"],"prefix":"10.1515","volume":"31","author":[{"given":"Jong Seo","family":"Yoon","sequence":"first","affiliation":[{"name":"Department of Pediatrics , Ajou University School of Medicine, Ajou University Hospital , Yeongtong-gu, Suwon , Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheol Hwan","family":"So","sequence":"additional","affiliation":[{"name":"Department of Pediatrics , Wonkwang University School of Medicine, Wonkwang University Hospital , Iksan, Jeonbuk , Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hae Sang","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics , Ajou University School of Medicine, Ajou University Hospital , Yeongtong-gu, Suwon , Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Soon","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics , Ajou University School of Medicine, Ajou University Hospital , San 5, Wonchon-dong, Yeongtong-gu , Suwon 443-721 , Republic of Korea , Phone: +82-31-219-5166, Fax: +82-31-219-5169"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2018,4,13]]},"reference":[{"key":"2021021322185982247_j_jpem-2017-0463_ref_001_w2aab3b7c29b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Cowie CC, Rust KF, Byrd-Holt DD, Gregg EW, Ford ES, et al. 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