{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T05:10:13Z","timestamp":1693372213716},"reference-count":12,"publisher":"Walter de Gruyter GmbH","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,2,25]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Resistance to thyroid hormone (RTH) commonly presents with goiter, attention deficit hyperactivity disorder (ADHD), short stature and tachycardia. However, due to its variable presentation with subtle clinical features, a third of the cases are mistreated, typically as hyperthyroidism.<\/jats:p>\n <\/jats:sec>\n \n Case presentation<\/jats:title>\n A 15-year-old female with ADHD and oligomenorrhea was initially diagnosed as Hashimoto\u2019s thyroiditis but found to have a rare heterozygous mutation in c803 C>G (p Ala 268 Gly) in the THR\u03b2<\/jats:italic> gene, confirming resistance to thyroid hormone.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Fluctuating thyroid function tests in addition to thyroid peroxidase antibody (TPO Ab) positivity complicated the diagnosis of RTH, initially diagnosed as Hashimoto\u2019s thyroiditis. A high index of suspicion is needed to prevent misdiagnosis and mistreatment.<\/jats:p>\n <\/jats:sec>","DOI":"10.1515\/jpem-2018-0284","type":"journal-article","created":{"date-parts":[[2019,1,25]],"date-time":"2019-01-25T09:08:39Z","timestamp":1548407319000},"page":"203-206","source":"Crossref","is-referenced-by-count":3,"title":["Challenging diagnosis of thyroid hormone resistance initially as Hashimoto\u2019s thyroiditis"],"prefix":"10.1515","volume":"32","author":[{"given":"Tong Wooi","family":"Ch\u2019ng","sequence":"first","affiliation":[{"name":"Department of Pediatrics , Division of Pediatric Endocrinology, SUNY Downstate Medical Center , Brooklyn, NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivian L.","family":"Chin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics , Division of Pediatric Endocrinology, SUNY Downstate Medical Center , Brooklyn, NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2019,1,25]]},"reference":[{"key":"2023040100395060367_j_jpem-2018-0284_ref_001_w2aab2b8c17b1b7b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Weiss RE, Dumitrescu A, Refetoff S. 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