{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T13:40:22Z","timestamp":1649166022787},"reference-count":44,"publisher":"Walter de Gruyter GmbH","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,12,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec id=\"j_jpem-2018-0340_s_999\">\n<jats:title id=\"d3868931e37897\">Background<\/jats:title>\n<jats:p>Hypertrophic cardiomyopathy (HCM) in childhood is a rare diagnosis, and associations with adrenocortical tumors (ACTs) have been rarely reported in the pediatric literature.<\/jats:p><\/jats:sec>\n<jats:sec id=\"j_jpem-2018-0340_s_998\">\n<jats:title id=\"d3868931e37905\">Case presentation<\/jats:title>\n<jats:p>We present a case of a 5-month-old who presented with HCM and during the evaluation for hypertension was found to have elevated glucocorticoids, mineralocorticoids, androgens and urine metanephrines. During preoperative evaluation, he developed shock followed by cardiogenic collapse requiring extracorporeal membrane oxygenation (ECMO); however, he did not survive. Pathology revealed an ACT with hormone production that contributed to his demise.<\/jats:p><\/jats:sec>\n<jats:sec id=\"j_jpem-2018-0340_s_997\">\n<jats:title id=\"d3868931e37913\">Conclusions<\/jats:title>\n<jats:p>Adrenocortical tumors associated with hypertrophic cardiomyopathy can be life-threatening. We discuss the complex interplay of unrestricted cortical hormone production in the setting of hypertrophic cardiomyopathy that may lead to rapid decline and poor clinical outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1515\/jpem-2018-0340","type":"journal-article","created":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T09:03:50Z","timestamp":1540285430000},"page":"1371-1376","source":"Crossref","is-referenced-by-count":0,"title":["Multi-disciplinary evaluation of a 5-month-old with hypertrophic cardiomyopathy related to a functional adrenocortical tumor"],"prefix":"10.1515","volume":"31","author":[{"given":"Laura M.","family":"Nally","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin","family":"Conner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon","family":"Paige","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly L.","family":"Mooney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urs","family":"Naber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Richards","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gail","family":"Wright","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref231","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1111\/ped.12702","article-title":"Adrenocortical tumor with precocious puberty in a 2-month-old girl","volume":"57","year":"2015","journal-title":"Pediatr Int"},{"key":"ref291","doi-asserted-by":"crossref","first-page":"e535","DOI":"10.1542\/peds.2012-2692","article-title":"Hypertrophic obstructive cardiomyopathy in an infant with an adrenocortical 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