{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T23:52:51Z","timestamp":1787961171544,"version":"build-2784847793"},"reference-count":7,"publisher":"Walter de Gruyter GmbH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,3,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The objective of this short communication was the relationship between vitamin D and precocious puberty (PP). In this study, a comprehensive search of multiple databases was performed to identify studies focused on the association between vitamin D deficiency and PP. Studies that compared serum vitamin D levels between patients with PP and controls were selected for the systematic meta-analysis. The main outcome was the mean difference in serum vitamin D levels between PP and controls. Vitamin D-deficient subjects were more likely to develop PP. Our findings suggest that PP may be linked to vitamin D deficiency. Thus, providing supplements of vitamin D to PP patients may improve their nutritional status and prevent diseases. But, the amount of vitamin D required is uncertain, so it is important to be careful when taking vitamin D supplements.<\/jats:p>","DOI":"10.1515\/jpem-2019-0388","type":"journal-article","created":{"date-parts":[[2020,2,18]],"date-time":"2020-02-18T09:03:21Z","timestamp":1582016601000},"page":"427-429","source":"Crossref","is-referenced-by-count":21,"title":["The association between vitamin D levels and precocious puberty: a meta-analysis"],"prefix":"10.1515","volume":"33","author":[{"given":"Shanshan","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Immunology, College of Basic Medical Sciences , Jilin University , Changchun , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xun","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Immunology, College of Basic Medical Sciences , Jilin University , Changchun , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanxin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Immunology, College of Basic Medical Sciences , Jilin University , Changchun , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoumeng","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health , Jilin University , Changchun , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Immunology, College of Basic Medical Sciences, Jilin University , 126 Xinmin Avenue, Changchun 130021 , China , Phone: +86-431-8561-9476"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Food Hygiene, School of Public Health , Jilin University , 1163 Xinmin Avenue , Changchun 130021 , China , Phone: +86-431-8561-9455"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2020,2,18]]},"reference":[{"key":"2023040101053363189_j_jpem-2019-0388_ref_001_w2aab3b7c35b1b6b1ab2b2b1Aa","doi-asserted-by":"crossref","unstructured":"Fuqua JS. Treatment and outcomes of precocious puberty: an update. J Clin Endocrinol Metab 2013;98:2198\u2013207.","DOI":"10.1210\/jc.2013-1024"},{"key":"2023040101053363189_j_jpem-2019-0388_ref_002_w2aab3b7c35b1b6b1ab2b2b2Aa","doi-asserted-by":"crossref","unstructured":"Zhao Y, Long W, Du C, Yang H, Wu S, et al. Prevalence of vitamin D deficiency in girls with idiopathic central precocious puberty. Front Med 2018;12:174\u201381.","DOI":"10.1007\/s11684-017-0544-5"},{"key":"2023040101053363189_j_jpem-2019-0388_ref_003_w2aab3b7c35b1b6b1ab2b2b3Aa","doi-asserted-by":"crossref","unstructured":"Cochran WG. The combination of estimates from different experiments. Biometrics 1954;10:101\u201329.","DOI":"10.2307\/3001666"},{"key":"2023040101053363189_j_jpem-2019-0388_ref_004_w2aab3b7c35b1b6b1ab2b2b4Aa","doi-asserted-by":"crossref","unstructured":"Perez-Fernandez R, Alonso M, Segura C, Munoz I, Garcia-Caballero T, et al. Vitamin D receptor gene expression in human pituitary gland. 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Vitamin-caused faulty perinatal hormonal imprinting and its consequences in adult age. 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