{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T20:19:05Z","timestamp":1778703545587,"version":"3.51.4"},"reference-count":35,"publisher":"Walter de Gruyter GmbH","issue":"7","funder":[{"DOI":"10.13039\/501100010215","name":"German Diabetes Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010215","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"German Federal Ministry of Education and Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Tuebinger Program for the Advancement of Women in Science"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpem-2019-0517_abs_001_w2aab3b7c17b1b6b1aab1c16b2Aa\">\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Accumulating evidence suggests a relationship between sleep alterations and overweight\/obesity in children. Our aim was to investigate the association of sleep measures other than obstructive sleep apnea or sleep duration with overweight\/obesity and metabolic function in children.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2019-0517_abs_002_w2aab3b7c17b1b6b1aab1c16b3Aa\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We conducted a prospective cohort study in school- aged children (aged 5 to 8 years, prepubertal, and 12 to 15 years, pubertal) with overweight\/obesity and normal-weight children. All children underwent a standardized in-laboratory polysomnography followed by a fasting blood assessment for glucose and metabolic testing. Subjective sleep measures were investigated by a 7-day sleep diary and questionnaire. We analyzed prepubertal and pubertal groups separately using logistic regression and partial correlation analyses.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2019-0517_abs_003_w2aab3b7c17b1b6b1aab1c16b4Aa\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 151 participants were analyzed. Overweight\/obese children had significantly higher odds for arousal index (prepubertal children: 1.28, Confidence interval (CI): 1.06, 1.67; pubertal children: 1.65, CI: 1.19, 2.29) than normal-weight children, independent of age and gender. In prepubertal children, arousal-index was positively associated with C-peptide (r=0.30, p=0.01), whereas Minimum O2 saturation was negatively associated with triglycerides (r=\u22120.34, p=0.005), adjusting for age and sex. However, associations were attenuated by further adjustment for body mass index standard deviation scores (BMI-SDS). In pubertal children, higher level of apnea-hypopnea-index and pCO2 predicted increased lipoprotein (a) levels (r=0.35, p=0.03 and r=0.40, p=0.01, respectively), independent of age, sex, and BMI-SDS. A negative association was found between pCO2 and high-density lipoprotein (HDL)-cholesterol (r=\u22120.40, p=0.01).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2019-0517_abs_004_w2aab3b7c17b1b6b1aab1c16b5Aa\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Overall, we report that sleep quality as measured by arousal index may be compromised by overweight and obesity in children and warrants attention in future intervention programs.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpem-2019-0517","type":"journal-article","created":{"date-parts":[[2020,7,10]],"date-time":"2020-07-10T12:57:11Z","timestamp":1594385831000},"page":"845-852","source":"Crossref","is-referenced-by-count":6,"title":["Association of sleep characteristics with adiposity markers in children"],"prefix":"10.1515","volume":"33","author":[{"given":"Theresa","family":"Herttrich","sequence":"first","affiliation":[{"name":"Department of Palliative Medicine , Munich University Hospital , Munich , Germany"},{"name":"Hospital for Children and Adolescents, Department of Women and Child Health and Center for Pediatric Research , Leipzig University , Leipzig , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johann","family":"Daxer","sequence":"additional","affiliation":[{"name":"Hospital for Children and Adolescents, Department of Women and Child Health and Center for Pediatric Research , Leipzig University , Leipzig , Germany"},{"name":"Department of Neurology , Hospital Stuttgart , Stuttgart , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Hiemisch","sequence":"additional","affiliation":[{"name":"Hospital for Children and Adolescents, Department of Women and Child Health and Center for Pediatric Research , Leipzig University , Leipzig , Germany"},{"name":"LIFE Leipzig Research Center for Civilization Diseases , Leipzig University , Leipzig , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Kluge","sequence":"additional","affiliation":[{"name":"Hospital for Children and Adolescents, Department of Women and Child Health and Center for Pediatric Research , Leipzig University , Leipzig , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Merkenschlager","sequence":"additional","affiliation":[{"name":"Hospital for Children and Adolescents, Department of Women and Child Health and Center for Pediatric Research , Leipzig University , Leipzig , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fcrgen","family":"Kratzsch","sequence":"additional","affiliation":[{"name":"IFB Adiposity Diseases , Leipzig University , Leipzig , Germany"},{"name":"Institute of Laboratory Medicine , Leipzig University , Leipzig , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathrin","family":"Scheuermann","sequence":"additional","affiliation":[{"name":"Hospital for Children and Adolescents, Department of Women and Child Health and Center for Pediatric Research , Leipzig University , Leipzig , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oskar G.","family":"Jenni","sequence":"additional","affiliation":[{"name":"Child Development Center , University Children\u2019s Hospital Zurich , Zurich , Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antje","family":"K\u00f6rner","sequence":"additional","affiliation":[{"name":"Hospital for Children and Adolescents, Department of Women and Child Health and Center for Pediatric Research , Leipzig University , Leipzig , Germany"},{"name":"LIFE Leipzig Research Center for Civilization Diseases , Leipzig University , Leipzig , Germany"},{"name":"IFB Adiposity Diseases , Leipzig University , Leipzig , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wieland","family":"Kiess","sequence":"additional","affiliation":[{"name":"Hospital for Children and Adolescents, Department of Women and Child Health and Center for Pediatric Research , Leipzig University , Leipzig , Germany"},{"name":"LIFE Leipzig Research Center for Civilization Diseases , Leipzig University , Leipzig , Germany"},{"name":"IFB Adiposity Diseases , Leipzig University , Leipzig , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirja","family":"Quante","sequence":"additional","affiliation":[{"name":"IFB Adiposity Diseases , Leipzig University , Leipzig , Germany"},{"name":"Department of Neonatology , University of Tuebingen , Tuebingen , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2020,7,5]]},"reference":[{"key":"2023040101122165809_j_jpem-2019-0517_ref_001_w2aab3b7c17b1b6b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Cappuccio, FP, Taggart, FM, Kandala, N-B, Currie, A, Peile, E, Stranges, S, et al. 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