{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T12:47:18Z","timestamp":1772110038187,"version":"3.50.1"},"reference-count":27,"publisher":"Walter de Gruyter GmbH","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpem-2022-0151_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Excessive adiposity is believed to contribute to insulin resistance, resulting in more complex metabolic outcomes and poorer glycaemic control. This study aimed to determine the prevalence of overweight\/obese, excessive adiposity, and metabolic syndrome in type 1 diabetes mellitus (T1DM) children, who were from a relatively overweight\/obese population, and to assess the effects on glycaemic control.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2022-0151_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A cross-sectional study was conducted from November 2019 to August 2020 on T1DM children between 6 and 18\u00a0years old who attended the Paediatric Endocrine Clinic Putrajaya Hospital. Anthropometry and bioelectrical impedance analysis (Inbody 720) were measured to analyse their effects towards glycated haemoglobin (HbA<jats:sub>1c<\/jats:sub>) via SPSS 21.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2022-0151_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 63 T1DM were recruited with an equal male-to-female ratio. The mean age was 12.4\u00a0\u00b1\u00a03.3 years old with a mean HbA<jats:sub>1c<\/jats:sub> of 9.8\u00a0\u00b1\u00a02.0%. The prevalence of overweight\/obese and excessive body fat was 17.5 and 34.9%, respectively. Only 3 (6.8%) fulfilled the metabolic syndrome criteria. The waist circumference had a significant relationship with HbA<jats:sub>1c<\/jats:sub>. Every 10\u00a0cm increment of waist circumference was predicted to raise HbA<jats:sub>1c<\/jats:sub> by 0.8. The odds ratio of having abdominal obesity among T1DM with excessive body fat was 9.3 times.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2022-0151_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Abdominal obesity is significantly associated with a poorer glycaemic control in T1DM children. Monitoring of waist circumference should be considered as part of the routine diabetic care.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpem-2022-0151","type":"journal-article","created":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T07:08:42Z","timestamp":1666336122000},"page":"1474-1480","source":"Crossref","is-referenced-by-count":11,"title":["Effect of obesity and excessive body fat on glycaemic control in paediatric type 1 diabetes"],"prefix":"10.1515","volume":"35","author":[{"given":"Pian Pian","family":"Tee","sequence":"first","affiliation":[{"name":"Paediatric Endocrine Unit , Putrajaya , Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeanne Sze Lyn","family":"Wong","sequence":"additional","affiliation":[{"name":"Paediatric Endocrine Unit , Putrajaya , Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nalini M.","family":"Selveindran","sequence":"additional","affiliation":[{"name":"Paediatric Endocrine Unit , Putrajaya , Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet Yeow Hua","family":"Hong","sequence":"additional","affiliation":[{"name":"Paediatric Endocrine Unit , Putrajaya , Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2022,10,21]]},"reference":[{"key":"2023040100361117334_j_jpem-2022-0151_ref_001","doi-asserted-by":"crossref","unstructured":"Conway, B, Miller, RG, Costacou, T, Fried, L, Kelsey, S, Evans, RW, et al.. 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