{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T04:51:05Z","timestamp":1747198265329,"version":"3.40.5"},"reference-count":10,"publisher":"Walter de Gruyter GmbH","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We present a 9-year-old boy with diabetes insipidus. The boy is treated with desmopressin (DDAVP) therapy. Under this therapy, the drinking quantity and the\u00a0laboratory parameters were normal. No nocturia occurred any more. In the context of a clinically mild infection with\u00a0SARS-CoV-2, the duration of action of DDAVP was significantly prolonged (approximately +50%). The original dosage was then reintroduced and\u00a0was still sufficient until months later. A possible connection to the infection with SARS-CoV-2 can be suspected. Our case report should make physicians who\u00a0care for patients with diabetes insipidus aware of such a possible prolongation of the effect of DDAVP. More frequent monitoring may be needed in such patients to assess the risk of symptomatic dilutional hyponatremia.<\/jats:p>","DOI":"10.1515\/jpem-2022-0422","type":"journal-article","created":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T16:32:48Z","timestamp":1665765168000},"page":"1544-1546","source":"Crossref","is-referenced-by-count":0,"title":["Infection with SARS-CoV-2 may alter the half-life of desmopressin (DDAVP) in patients with central diabetes insipidus"],"prefix":"10.1515","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3670-2453","authenticated-orcid":false,"given":"Ilja","family":"Dubinski","sequence":"first","affiliation":[{"name":"Department of Pediatrics , Dr. von Hauner Children\u2019s Hospital, University Hospital, LMU Munich , Munich , Bavaria , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne","family":"Bechtold-Dalla Pozza","sequence":"additional","affiliation":[{"name":"Department of Pediatrics , Dr. von Hauner Children\u2019s Hospital, University Hospital, LMU Munich , Munich , Bavaria , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heinrich","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department of Pediatrics , Dr. von Hauner Children\u2019s Hospital, University Hospital, LMU Munich , Munich , Bavaria , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2022,10,17]]},"reference":[{"key":"2023040100361116767_j_jpem-2022-0422_ref_001","doi-asserted-by":"crossref","unstructured":"Maghnie, M, Cosi, G, Genovese, E, Manca-Bitti, ML, Cohen, A, Zecca, S, et al.. 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