{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T16:43:20Z","timestamp":1758818600460,"version":"3.40.5"},"reference-count":18,"publisher":"Walter de Gruyter GmbH","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpem-2023-0300_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Many thyroid disorders in children demand long-term therapy. The parent\u2019s understanding of the child\u2019s condition is of utmost importance for adherence to treatment. The study objective was to assess the knowledge, medication adherence, reasons for non-adherence, and their relationship with various clinical parameters.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2023-0300_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>An exploratory, cross-sectional study with a total enumeration sampling technique was conducted between July 2022 and September 2022. Children and young adults aged\u00a0\u226418 years who were diagnosed with a thyroid disorder and taking medications for at least 3\u00a0months were included. Data were collected by interviewing parents using the Adherence to Refills and Medications Scale (ARMS) and structured knowledge questionnaire.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2023-0300_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Parents of 102 children were interviewed. The mean age of the children was 9.2\u00a0\u00b1\u00a00.4 years; 58 (57\u202f%) were girls. The mean duration of treatment was 5.5\u00a0\u00b1\u00a00.3 years. Many (66\u202f%) informants were mothers. Three-fourths (75.5\u202f%) of parents were educated up to senior secondary and above. Most (91.2\u202f%) of parents had poor knowledge about the disease and its management. Poor disease knowledge was significantly linked to lower education (p&lt;0.001). Nonetheless, strong adherence (&gt;80\u202f%) was noted on the ARMS scale. No significant correlation was found between physical growth, thyroid function, and adherence\/knowledge (p-values 0.20\u20130.71).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2023-0300_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The caregivers\u2019 knowledge of thyroid disorders was poor and related to their educational level. There is a need to use clear language and ensure that parents have an adequate understanding of their child\u2019s condition. Healthcare professionals should assess and address gaps in parental knowledge and adherence.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpem-2023-0300","type":"journal-article","created":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T02:10:37Z","timestamp":1698631837000},"page":"1169-1174","source":"Crossref","is-referenced-by-count":2,"title":["Caregivers\u2019 knowledge and medication adherence in children with thyroid disorders: an exploratory study"],"prefix":"10.1515","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0201-2748","authenticated-orcid":false,"given":"Neetu","family":"Gujjar","sequence":"first","affiliation":[{"name":"Post Graduate Institute of Medical Education & Research , Chandigarh , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2883-271X","authenticated-orcid":false,"given":"Poonam","family":"Verma","sequence":"additional","affiliation":[{"name":"Post Graduate Institute of Medical Education & Research , Chandigarh , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9803-779X","authenticated-orcid":false,"given":"Latika","family":"Rohilla","sequence":"additional","affiliation":[{"name":"Department of Pediatrics , Post Graduate Institute of Medical Education & Research , Chandigarh , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shivalli","family":"Sirswal","sequence":"additional","affiliation":[{"name":"Post Graduate Institute of Medical Education & Research , Chandigarh , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Divya","family":"Sharma","sequence":"additional","affiliation":[{"name":"Post Graduate Institute of Medical Education & Research , Chandigarh , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3279-6002","authenticated-orcid":false,"given":"Devi","family":"Dayal","sequence":"additional","affiliation":[{"name":"Endocrinology and Diabetes Unit, Department of Pediatrics , Post Graduate Institute of Medical Education & Research , Chandigarh , India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2023,10,30]]},"reference":[{"key":"2023112810420460603_j_jpem-2023-0300_ref_001","doi-asserted-by":"crossref","unstructured":"Hanley, P, Lord, K, Bauer, AJ. Thyroid disorders in children and adolescents: a review. JAMA Pediatr 2016;170:1008\u201319. https:\/\/doi.org\/10.1001\/jamapediatrics.2016.0486.","DOI":"10.1001\/jamapediatrics.2016.0486"},{"key":"2023112810420460603_j_jpem-2023-0300_ref_002","doi-asserted-by":"crossref","unstructured":"Dayal, D, Gupta, BM, Gupta, A. Thyroid disorders in children and adolescents: systematic mapping of global research over the past three decades. Thyroid Res Pract 2021;18:23\u201330. https:\/\/doi.org\/10.4103\/trp.trp_5_21.","DOI":"10.4103\/trp.trp_5_21"},{"key":"2023112810420460603_j_jpem-2023-0300_ref_003","doi-asserted-by":"crossref","unstructured":"Dayal, D, Prasad, R. Congenital hypothyroidism: current perspectives. 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J Indian Assoc Public Health Dent 2021;19:154\u20135. https:\/\/doi.org\/10.4103\/jiaphd.jiaphd_52_21.","DOI":"10.4103\/jiaphd.jiaphd_52_21"},{"key":"2023112810420460603_j_jpem-2023-0300_ref_012","doi-asserted-by":"crossref","unstructured":"Kripalani, S, Risser, J, Gatti, ME, Jacobson, TA. Development and evaluation of the Adherence to Refills and Medications Scale (ARMS) among low-literacy patients with chronic disease. Value Health 2009;12:118\u201323. https:\/\/doi.org\/10.1111\/j.1524-4733.2008.00400.x.","DOI":"10.1111\/j.1524-4733.2008.00400.x"},{"key":"2023112810420460603_j_jpem-2023-0300_ref_013","doi-asserted-by":"crossref","unstructured":"Elnaem, MH, Irwan, NA, Abubakar, U, Syed Sulaiman, SA, Elrggal, ME, Cheema, E. Impact of medication regimen simplification on medication adherence and clinical outcomes in patients with long-term medical conditions. 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