{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T14:44:14Z","timestamp":1773413054511,"version":"3.50.1"},"reference-count":29,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpem-2023-0550_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The aim of our study is to examine the emotional, behavioral problems, and psychiatric symptoms of children diagnosed with Graves\u2019 disease (GD), to assess their quality of life, and to compare with control group.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2023-0550_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The research was planned as a cross-sectional study and included 16 patients with GD (13 female and three male) and 29 healthy children for control group (19 female and 10 male). Sociodemographic form, Pediatric Quality of Life Inventory, Revised Child Anxiety and Depression Scale-Child Version (RCADS-CV), Strengths and Difficulties Questionnaire (SDQ), Turgay DSM-IV-Based Child and Adolescent Behavior Disorders Screening and Rating Scale (T-DSM-IV-S), and Affective Reactivity Index scale were applied to the children and their families.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2023-0550_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Eighty one\u202fpercent of GD group (GG) (n=13, mean age 15.1\u00a0\u00b1\u00a02.2) and 66\u202f% of control group (CG) (n=19, 14.6\u00a0\u00b1\u00a02.2) were girls. No significant difference was found between GG and CG in terms of quality of life, anxiety, and depression scores. GG had higher scores in affective reactivity index, SDQ-P total score, and T-DSM-IV-S total scores (p values 0.039; 0.009; 0.023, respectively). While no significant difference was detected in the T-DSM-IV-S-inattention and hyperactivity scores, significantly higher scores were detected in oppositional defiance and conduct disorder scores (p\u00a0values 0.172; 0.294; 0.019; 0.027, respectively).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2023-0550_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>In children with GD, irritability, oppositional defiant, and conduct disorder symptoms have been detected. Children with these mental health symptoms experience behavioral and emotional difficulties in their daily lives. It is important to follow up children with GD for possible comorbid psychiatric disorders.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpem-2023-0550","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T07:08:15Z","timestamp":1713769695000},"page":"445-450","source":"Crossref","is-referenced-by-count":5,"title":["Examination of quality of life and psychiatric symptoms in childhood Graves\u2019 disease"],"prefix":"10.1515","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8245-0176","authenticated-orcid":false,"given":"G\u00f6zde","family":"Yazkan Akg\u00fcl","sequence":"first","affiliation":[{"name":"Child and Adolescent Psychiatry Department, School of Medicine, Marmara University , \u0130stanbul , T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0598-3494","authenticated-orcid":false,"given":"\u00d6zge","family":"K\u00f6pr\u00fcl\u00fc","sequence":"additional","affiliation":[{"name":"Division of Pediatric Endocrinology, Tekirda\u011f IFC City Hospital , Tekirda\u011f , T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2024,4,22]]},"reference":[{"key":"2024081908520422802_j_jpem-2023-0550_ref_001","doi-asserted-by":"crossref","unstructured":"L\u00e9ger, J. 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