{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T21:48:13Z","timestamp":1793310493252,"version":"4.5.0"},"reference-count":42,"publisher":"Walter de Gruyter GmbH","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpem-2024-0467_abs_001\">\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>This study aimed to identify clinical features of girls referred to a pediatric endocrinology clinic for suspected precocious puberty, differentiate true precocious puberty from other variants, evaluate treatment status, and identify distinguishing factors between patient groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2024-0467_abs_002\">\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We retrospectively evaluated the records of 275 consecutive girls aged 0\u201310 years referred for suspected precocious puberty.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2024-0467_abs_003\">\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Among the patients, 30 (10.9\u202f%) were diagnosed with precocious puberty, 35 (12.7\u202f%) with premature adrenarche, 22 (8\u202f%) with premature thelarche, 33 (12\u202f%) with rapidly progressing early puberty, 108 (39.3\u202f%) with early puberty, and 47 (17.1\u202f%) had a normal diagnosis. Precocious puberty was associated with higher rates of overweight\/obesity (p=0.002), advanced bone age (p&lt;0.001), height SD, and mid-parental height SD difference (p&lt;0.001), as well as a history of preterm birth (p=0.041). Patients with rapidly progressing early puberty had mothers with a lower age at menarche (p=0.040). No significant differences were found for being born small for gestational age, maternal polycystic ovary syndrome, screen time, and junk food consumption (p&gt;0.05). Treatment was recommended for 32 patients (11.6\u202f%), including 11 with precocious puberty and 21 with rapidly progressing early puberty.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpem-2024-0467_abs_004\">\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Most patients referred for early pubertal development are diagnosed with normal puberty or its variants. Assessing preterm birth, early maternal menarche age, and advanced bone age helps identify true precocious puberty and rapidly progressing early puberty, aiding timely treatment.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpem-2024-0467","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T09:44:31Z","timestamp":1738230271000},"source":"Crossref","is-referenced-by-count":2,"title":["Differentiating true precocious puberty and puberty variants in consecutive 275 girls: a single center experience"],"prefix":"10.1515","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7355-5408","authenticated-orcid":false,"given":"Emre","family":"Sar\u0131kaya","sequence":"first","affiliation":[{"name":"Department of Pediatric Endocrinology , Kocaeli City Hospital , Kocaeli , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4040-7908","authenticated-orcid":false,"given":"Fatih","family":"Kilci","sequence":"additional","affiliation":[{"name":"Department of Pediatric Endocrinology , Kocaeli City Hospital , Kocaeli , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2025,1,31]]},"reference":[{"key":"2025020413135241086_j_jpem-2024-0467_ref_001","doi-asserted-by":"crossref","unstructured":"Marshall, WA, Tanner, JM. Variations in pattern of pubertal changes in girls. Arch Dis Child 1969;44:291\u2013303. https:\/\/doi.org\/10.1136\/adc.44.235.291.","DOI":"10.1136\/adc.44.235.291"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_002","doi-asserted-by":"crossref","unstructured":"Herman-Giddens, ME, Slora, EJ, Wasserman, RC, Bourdony, CJ, Bhapkar, MV, Koch, GG, et al.. Secondary sexual characteristics and menses in young girls seen in office practice: a study from the pediatric research in office settings network. Pediatrics 1997;99:505\u201312. https:\/\/doi.org\/10.1542\/peds.99.4.505.","DOI":"10.1542\/peds.99.4.505"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_003","doi-asserted-by":"crossref","unstructured":"Aksglaede, L, S\u00f8rensen, K, Petersen, JH, Skakkebaek, NE, Juul, A. Recent decline in age at breast development: the Copenhagen puberty study. Pediatrics 2009;123:e932\u20139. https:\/\/doi.org\/10.1542\/peds.2008-2491.","DOI":"10.1542\/peds.2008-2491"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_004","doi-asserted-by":"crossref","unstructured":"Roelants, M, Hauspie, R, Hoppenbrouwers, K. References for growth and pubertal development from birth to 21 years in Flanders, Belgium. Ann Hum Biol 2009;36:680\u201394. https:\/\/doi.org\/10.3109\/03014460903049074.","DOI":"10.3109\/03014460903049074"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_005","doi-asserted-by":"crossref","unstructured":"Biro, FM, Greenspan, LC, Galvez, MP, Pinney, SM, Teitelbaum, S, Windham, GC, et al.. Onset of breast development in a longitudinal cohort. Pediatrics 2013;132:1019\u201327. https:\/\/doi.org\/10.1542\/peds.2012-3773.","DOI":"10.1542\/peds.2012-3773"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_006","doi-asserted-by":"crossref","unstructured":"Eckert-Lind, C, Busch, AS, Petersen, JH, Biro, FM, Butler, G, Br\u00e4uner, EV, et al.. Worldwide secular trends in age at pubertal onset assessed by breast development among girls: a systematic review and meta-analysis. JAMA Pediatr 2020;174:e195881. https:\/\/doi.org\/10.1001\/jamapediatrics.2019.5881.","DOI":"10.1001\/jamapediatrics.2019.5881"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_007","doi-asserted-by":"crossref","unstructured":"Willemsen, RH, Elleri, D, Williams, RM, Ong, KK, Dunger, DB. Pros and cons of GnRHa treatment for early puberty in girls. Nat Rev Endocrinol 2014;10:352\u201363. https:\/\/doi.org\/10.1038\/nrendo.2014.40.","DOI":"10.1038\/nrendo.2014.40"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_008","doi-asserted-by":"crossref","unstructured":"Tenedero, CB, Oei, K, Palmert, MR. An approach to the evaluation and management of the obese child with early puberty. J Endocr Soc 2021;6:bvab173. https:\/\/doi.org\/10.1210\/jendso\/bvab173.","DOI":"10.1210\/jendso\/bvab173"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_009","doi-asserted-by":"crossref","unstructured":"Atay, Z, Turan, S, Guran, T, Furman, A, Bereket, A. The prevalence and risk factors of premature thelarche and pubarche in 4- to 8-year-old girls. Acta Paediatr 2012;101:e71\u20135. https:\/\/doi.org\/10.1111\/j.1651-2227.2011.02444.x.","DOI":"10.1111\/j.1651-2227.2011.02444.x"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_010","doi-asserted-by":"crossref","unstructured":"Shi, L, Jiang, Z, Zhang, L. Childhood obesity and central precocious puberty. Front Endocrinol 2022;13:1056871. https:\/\/doi.org\/10.3389\/fendo.2022.1056871.","DOI":"10.3389\/fendo.2022.1056871"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_011","doi-asserted-by":"crossref","unstructured":"K\u0131l\u0131\u00e7, A, Durmu\u015f, MS, \u00dcn\u00fcvar, E, Y\u0131ld\u0131z, I, Ayd\u0131n, BK, U\u00e7ar, A, et al.. Clinical and laboratory characteristics of children referred for early puberty: preponderance in 7-8 years of age. J Clin Res Pediatr Endocrinol 2012;4:208\u201312. https:\/\/doi.org\/10.4274\/jcrpe.736.","DOI":"10.4274\/Jcrpe.736"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_012","doi-asserted-by":"crossref","unstructured":"Lian, Q, Mao, Y, Luo, S, Zhang, S, Tu, X, Zuo, X, et al.. Puberty timing associated with obesity and central obesity in Chinese Han girls. 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J Clin Endocrinol Metab 2011;96:525\u201333. https:\/\/doi.org\/10.1210\/jc.2010-1523.","DOI":"10.1210\/jc.2010-1523"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_017","doi-asserted-by":"crossref","unstructured":"Cheng, TS, Ong, KK, Biro, FM. Trends toward earlier puberty timing in girls and its likely mechanisms. J Pediatr Adolesc Gynecol 2022;35:527\u201331. https:\/\/doi.org\/10.1016\/j.jpag.2022.04.009.","DOI":"10.1016\/j.jpag.2022.04.009"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_018","doi-asserted-by":"crossref","unstructured":"Pang, B, Wang, Q, Yang, M, Xue, M, Zhang, Y, Deng, X, et al.. Identification and optimization of contributing factors for precocious puberty by machine\/deep learning methods in Chinese girls. Front Endocrinol 2022;13:892005. https:\/\/doi.org\/10.3389\/fendo.2022.892005.","DOI":"10.3389\/fendo.2022.892005"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_019","doi-asserted-by":"crossref","unstructured":"K\u0131l\u0131n\u00e7 U\u011furlu, A, Bideci, A, Demirel, MA, Take Kaplano\u011flu, G, Dayan\u0131r, D, G\u00fclbahar, \u00d6, et al.. Effects of blue light on puberty and ovary in female rats. J Clin Res Pediatr Endocrinol 2023;15:365\u201374. https:\/\/doi.org\/10.4274\/jcrpe.galenos.2023.2022-12-1.","DOI":"10.4274\/jcrpe.galenos.2023.2022-12-1"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_020","doi-asserted-by":"crossref","unstructured":"Neyzi, O, Bundak, R, G\u00f6k\u00e7ay, G, G\u00fcn\u00f6z, H, Furman, A, Darendeliler, F, et al.. Reference values for weight, height, head circumference, and body mass index in Turkish children. J Clin Res Pediatr Endocrinol 2015;7:280\u201393. https:\/\/doi.org\/10.4274\/jcrpe.2183.","DOI":"10.4274\/jcrpe.2183"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_021","doi-asserted-by":"crossref","unstructured":"Berbero\u011flu, M. Precocious puberty and normal variant puberty: definition, etiology, diagnosis and current management. J Clin Res Pediatr Endocrinol 2009;1:164\u201374. https:\/\/doi.org\/10.4274\/jcrpe.v1i4.3.","DOI":"10.4274\/jcrpe.v1i4.3"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_022","doi-asserted-by":"crossref","unstructured":"Latronico, AC, Brito, VN, Carel, JC. Causes, diagnosis, and treatment of central precocious puberty. Lancet Diabetes Endocrinol 2016;4:265\u201374. https:\/\/doi.org\/10.1016\/S2213-8587(15)00380-0.","DOI":"10.1016\/S2213-8587(15)00380-0"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_023","doi-asserted-by":"crossref","unstructured":"Bereket, A. A critical appraisal of the effect of gonadotropin-releasing hormon analog treatment on adult height of girls with central precocious puberty. J Clin Res Pediatr Endocrinol 2017;9:33\u201348. https:\/\/doi.org\/10.4274\/jcrpe.2017.S004.","DOI":"10.4274\/jcrpe.2017.S004"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_024","unstructured":"Greulich, WW, Idell Pyle, S. Radiographic atlas of skeletal development of the hand and wrist: based on the Brush Foundation study of human growth and development initiated by T. Wingate Todd, MB, Ch. B., FRCS. Redwood City CA: Stanford University Press; 1950."},{"key":"2025020413135241086_j_jpem-2024-0467_ref_025","doi-asserted-by":"crossref","unstructured":"Kaplowitz, P. Clinical characteristics of 104 children referred for evaluation of precocious puberty. J Clin Endocrinol Metab 2004;89:3644\u201350. https:\/\/doi.org\/10.1210\/jc.2003-031532.","DOI":"10.1210\/jc.2003-031532"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_026","doi-asserted-by":"crossref","unstructured":"Mogensen, SS, Aksglaede, L, Mouritsen, A, S\u00f8rensen, K, Main, KM, Gideon, P, et al.. Diagnostic work-up of 449 consecutive girls who were referred to be evaluated for precocious puberty. J Clin Endocrinol Metab 2011;96:1393\u2013401. https:\/\/doi.org\/10.1210\/jc.2010-2745.","DOI":"10.1210\/jc.2010-2745"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_027","doi-asserted-by":"crossref","unstructured":"Eklio\u011flu, BS, Atabek, ME, Aky\u00fcrek, N, Sar\u0131kaya, E. The etiologic distribution and clinical features of cases presenting with the findings of puberty to the pediatric endocrinology clinic. Turkish J Pediatr Dis 2016;10:233\u20136. https:\/\/doi.org\/10.12956\/tjpd.2016.212.","DOI":"10.12956\/tjpd.2016.212"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_028","doi-asserted-by":"crossref","unstructured":"Kaplowitz, PB, Slora, EJ, Wasserman, RC, Pedlow, SE, Herman-Giddens, ME. Earlier onset of puberty in girls: relation to increased body mass index and race. Pediatrics 2001;108:347\u201353. https:\/\/doi.org\/10.1542\/peds.108.2.347.","DOI":"10.1542\/peds.108.2.347"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_030","doi-asserted-by":"crossref","unstructured":"Rosenfield, RL, Lipton, RB, Drum, ML. Thelarche, pubarche, and menarche attainment in children with normal and elevated body mass index [published correction appears in Pediatrics. 2009 Apr;123(4):1255]. Pediatrics 2009;123:84\u20138. https:\/\/doi.org\/10.1542\/peds.2008-0146.","DOI":"10.1542\/peds.2008-0146"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_029","doi-asserted-by":"crossref","unstructured":"S\u00f8rensen, K, Juul, A. BMI percentile-for-age overestimates adiposity in early compared with late maturing pubertal children. Eur J Endocrinol 2015;173:227\u201335. https:\/\/doi.org\/10.1530\/EJE-15-0239.","DOI":"10.1530\/EJE-15-0239"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_031","doi-asserted-by":"crossref","unstructured":"Shahatah, MA, Jadkarim, AM, Banjar, RZ, Kabli, YO, Milyani, AA, Al-Agha, AE. The relationship between body weight and dietary habits with respect to the timing of puberty among Saudi children and adolescents. Ann Afr Med 2021;20:193\u20137. https:\/\/doi.org\/10.4103\/aam.aam_41_20.","DOI":"10.4103\/aam.aam_41_20"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_032","doi-asserted-by":"crossref","unstructured":"Suikkanen, J, Nurhonen, M, Cole, TJ, Paalanne, M, Matinolli, HM, Tikanm\u00e4ki, M, et al.. Preterm birth and subsequent timing of pubertal growth, menarche, and voice break. Pediatr Res 2022;92:199\u2013205. https:\/\/doi.org\/10.1038\/s41390-021-01690-5.","DOI":"10.1038\/s41390-021-01690-5"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_033","doi-asserted-by":"crossref","unstructured":"Persson, I, Ahlsson, F, Ewald, U, Tuvemo, T, Qingyuan, M, von Rosen, D, et al.. Influence of perinatal factors on the onset of puberty in boys and girls: implications for interpretation of link with risk of long term diseases. Am J Epidemiol 1999;150:747\u201355. https:\/\/doi.org\/10.1093\/oxfordjournals.aje.a010077.","DOI":"10.1093\/oxfordjournals.aje.a010077"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_034","doi-asserted-by":"crossref","unstructured":"Bocca-Tjeertes, IF, van Buuren, S, Bos, AF, Kerstjens, JM, Ten Vergert, EM, Reijneveld, SA. Growth of preterm and full-term children aged 0-4 years: integrating median growth and variability in growth charts. J Pediatr 2012;161:460\u20135.e1. https:\/\/doi.org\/10.1016\/j.jpeds.2012.03.016.","DOI":"10.1016\/j.jpeds.2012.03.016"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_035","doi-asserted-by":"crossref","unstructured":"Derraik, JG, Lundgren, M, Cutfield, WS, Ahlsson, F. Association between preterm birth and lower adult height in women. Am J Epidemiol 2017;185:48\u201353. https:\/\/doi.org\/10.1093\/aje\/kww116.","DOI":"10.1093\/aje\/kww116"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_036","doi-asserted-by":"crossref","unstructured":"Demirkale, ZH, Abali, ZY, Bas, F, Poyrazoglu, S, Bundak, R, Darendeliler, F. Comparison of the clinical and anthropometric features of treated and untreated girls with borderline early puberty. J Pediatr Adolesc Gynecol 2019;32:264\u201370. https:\/\/doi.org\/10.1016\/j.jpag.2019.01.003.","DOI":"10.1016\/j.jpag.2019.01.003"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_037","doi-asserted-by":"crossref","unstructured":"Salardi, S, Cacciari, E, Mainetti, B, Mazzanti, L, Pirazzoli, P. Outcome of premature thelarche: relation to puberty and final height. Arch Dis Child 1998;79:173\u20134. https:\/\/doi.org\/10.1136\/adc.79.2.173.","DOI":"10.1136\/adc.79.2.173"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_038","doi-asserted-by":"crossref","unstructured":"Wohlfahrt-Veje, C, Mouritsen, A, Hagen, CP, Tinggaard, J, Mieritz, MG, Boas, M, et al.. Pubertal onset in boys and girls is influenced by pubertal timing of both parents. J Clin Endocrinol Metab 2016;101:2667\u201374. https:\/\/doi.org\/10.1210\/jc.2016-1073.","DOI":"10.1210\/jc.2016-1073"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_039","doi-asserted-by":"crossref","unstructured":"Pr\u00e9t\u00e9, G, Couto-Silva, AC, Trivin, C, Brauner, R. Idiopathic central precocious puberty in girls: presentation factors. BMC Pediatr 2008;8:27. https:\/\/doi.org\/10.1186\/1471-2431-8-27.","DOI":"10.1186\/1471-2431-8-27"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_040","doi-asserted-by":"crossref","unstructured":"Lunddorf, LLH, Arendt, LH, Ernst, A, Brix, N, Knudsen, UB, Olsen, J, et al.. Maternal polycystic ovarian syndrome and pubertal development in daughters and sons: a population-based cohort study. Hum Reprod 2022;37:2623\u201334. https:\/\/doi.org\/10.1093\/humrep\/deac197.","DOI":"10.1093\/humrep\/deac197"},{"key":"2025020413135241086_j_jpem-2024-0467_ref_041","unstructured":"Kustin, K, Wahyuningtyias, F, Munawir, A. The effects of junk food consumption on incidence of early puberty in adolescent females. Health Notions 2017;1:408\u201313. https:\/\/doi.org\/10.33846\/hn.v1i4.80."},{"key":"2025020413135241086_j_jpem-2024-0467_ref_042","doi-asserted-by":"crossref","unstructured":"Anita, S, Simanjuntak, YT. 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