{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T23:39:48Z","timestamp":1791848388938,"version":"4.3.4"},"reference-count":24,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jpem-2025-0033_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The study aimed to evaluate the impact of antenatal steroid administration, a key intervention for reducing early mortality and morbidity in preterm infants, on the development of metabolic bone disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpem-2025-0033_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single-center retrospective study was conducted in a Level III neonatal intensive care unit from October 2020 to December 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpem-2025-0033_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>It included 173 infants born before 32\u00a0weeks of gestation, with a mean birth weight of 1,338\u00a0\u00b1\u00a0293\u202fg. Metabolic bone disease, diagnosed at four weeks of age based on serum phosphorus and alkaline phosphatase levels, was identified in 26 (15\u202f%) of the infants. Regression analysis examined prenatal factors, including birth weight, intrauterine growth restriction, respiratory distress syndrome, gender, and antenatal steroid exposure, revealing that only lower birth weight was an independent risk factor for metabolic bone disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpem-2025-0033_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Antenatal steroid administration did not significantly influence the diagnosis of metabolic bone disease when assessed using biochemical markers at four weeks of age. These findings underscore the importance of birth weight in the risk profile for metabolic bone disease while indicating that antenatal steroids are not a contributing factor.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jpem-2025-0033","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T08:08:02Z","timestamp":1742198882000},"page":"509-513","source":"Crossref","is-referenced-by-count":2,"title":["The effect of antenatal steroids on metabolic bone disease of prematurity"],"prefix":"10.1515","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8758-7662","authenticated-orcid":false,"given":"Sara","family":"Erol","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Neonatology , Ankara Bilkent City Hospital , Ankara , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa Senol","family":"Akin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neonatology , Ankara Bilkent City Hospital , Ankara , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nihan Hilal","family":"Hosagasi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neonatology , Ankara Bilkent City Hospital , Ankara , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabriye","family":"Korkut","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neonatology , Ankara Bilkent City Hospital , Ankara , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2025,3,18]]},"reference":[{"key":"2026021616490275984_j_jpem-2025-0033_ref_001","doi-asserted-by":"crossref","unstructured":"McGoldrick, E, Stewart, F, Parker, R, Dalziel, SR. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev 2020;12:CD004454. https:\/\/doi.org\/10.1002\/14651858.CD004454.pub4.","DOI":"10.1002\/14651858.CD004454.pub4"},{"key":"2026021616490275984_j_jpem-2025-0033_ref_002","doi-asserted-by":"crossref","unstructured":"Jobe, AH, Goldenberg, RL, Kemp, MW. Antenatal corticosteroids: an updated assessment of anticipated benefits and potential risks. Am J Obstet Gynecol 2024;230:330\u20139. https:\/\/doi.org\/10.1016\/j.ajog.2023.09.013.","DOI":"10.1016\/j.ajog.2023.09.013"},{"key":"2026021616490275984_j_jpem-2025-0033_ref_003","doi-asserted-by":"crossref","unstructured":"Kemp, MW, Schmidt, AF, Jobe, AH. Optimizing antenatal corticosteroid therapy. 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