{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T14:13:55Z","timestamp":1783433635883,"version":"3.54.6"},"reference-count":10,"publisher":"Walter de Gruyter GmbH","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jpem-2025-0369_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This report presents a rare pediatric functional AO causing CS and androgen excess. It aims to discuss the diagnostic challenges of cortisol and DHEAS co-secretion, which may mimic adenomas or carcinomas. It also emphasizes the role of clinical, biochemical, and imaging assessments, as well as histological classification using LWB criteria, and the need for long-term follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpem-2025-0369_abs_002\">\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>A 17-year-old female presented with weight gain, moon facies, cushingoid striae, oligomenorrhea, and acne over six months. Examination showed hypertension, grade I obesity, cushingoid stigmata without virilization. Endocrine evaluation was confirmed ACTH independent CS due to right\u00a0AO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpem-2025-0369_abs_003\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This case illustrates functional AO as a rare cause of adolescent CS with androgen excess. Co-secretion patterns complicate diagnosis, imaging may not be definitive, and long-term follow-up is vital due to uncertain prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jpem-2025-0369","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T10:32:15Z","timestamp":1759228335000},"page":"86-90","source":"Crossref","is-referenced-by-count":0,"title":["Adrenal oncocytoma: an unusual etiology of Cushing\u2019s syndrome in an adolescent female"],"prefix":"10.1515","volume":"39","author":[{"given":"Saba Samad","family":"Memon","sequence":"first","affiliation":[{"name":"Department of Endocrinology Seth GS Medical College and KEM Hospital Parel , Mumbai , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6658-0269","authenticated-orcid":false,"given":"Manjunath Havalappa","family":"Dodamani","sequence":"additional","affiliation":[{"name":"Rukmini Hormone Superspeciality Centre , Bagalkot , Karnataka , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6627-4942","authenticated-orcid":false,"given":"Sanjay","family":"Chaudhari","sequence":"additional","affiliation":[{"name":"Department of Pathology , Pramukhswami Medical College , Karamsad , Gujarat , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8363-7773","authenticated-orcid":false,"given":"Zalak","family":"Parmar","sequence":"additional","affiliation":[{"name":"Department of Pathology , Pramukhswami Medical College , Karamsad , Gujarat , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaushal","family":"Patel","sequence":"additional","affiliation":[{"name":"Nephron Kidney Hospital , Anand , Gujarat , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suresh","family":"Bhoi","sequence":"additional","affiliation":[{"name":"Vivaan Imaging Centre , Anand , Gujarat , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6275-5650","authenticated-orcid":false,"given":"Ravikumar","family":"Shah","sequence":"additional","affiliation":[{"name":"Harikrushna Hormone Clinic , Anand , Gujarat , India"},{"name":"Department of Endocrinology , Currently Consultant Endocrinologist at Harikrushna Hormone Clinic , Anand , Gujarat , 388001 , India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2025,10,1]]},"reference":[{"key":"2026070713031934479_j_jpem-2025-0369_ref_001","doi-asserted-by":"crossref","unstructured":"Ferrigno, R, Hasenmajer, V, Caiulo, S, Minnetti, M, Mazzotta, P, Storr, HL, et al.. Paediatric Cushing\u2019s disease: epidemiology, pathogenesis, clinical management and outcome. Rev Endocr Metab Disord 2021;22:817\u201335. https:\/\/doi.org\/10.1007\/s11154-021-09626-4.","DOI":"10.1007\/s11154-021-09626-4"},{"key":"2026070713031934479_j_jpem-2025-0369_ref_002","doi-asserted-by":"crossref","unstructured":"Arnaldi, G, Martino, M. Androgens in cushing\u2019s syndrome. Front Horm Res 2019;53:77\u201391. https:\/\/doi.org\/10.1159\/000494904.","DOI":"10.1159\/000494904"},{"key":"2026070713031934479_j_jpem-2025-0369_ref_003","doi-asserted-by":"crossref","unstructured":"Kovacic, J, Louie-Johnsun, M. A rare case of co-secreting adrenocortical oncocytoma. Urol Case Rep 2023;46:102285. https:\/\/doi.org\/10.1016\/j.eucr.2022.102285.","DOI":"10.1016\/j.eucr.2022.102285"},{"key":"2026070713031934479_j_jpem-2025-0369_ref_004","doi-asserted-by":"crossref","unstructured":"Coppola Bottazzi, E, Gambardella, C, Mongardini, FM, Vanella, S, Noviello, A, Palma, T, et al.. 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