{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T01:09:37Z","timestamp":1780621777683,"version":"3.54.1"},"reference-count":31,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_jpem-2026-0101_abs_001\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to evaluate the clinical accuracy of automated BoneXpert (BX) vs. clinician-based Greulich-Pyle (GP) bone age (BA) assessments by comparing their respective predicted adult heights (PAH) with near-final height (NFH) in patients with congenital adrenal hyperplasia (CAH).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpem-2026-0101_abs_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Forty-seven patients with classic salt-wasting CAH diagnosed in the neonatal period who had reached NFH were included. Left hand-wrist radiographs obtained during the prepubertal period (6\u20139 years) were evaluated manually by two clinicians using the GP atlas and by the BX-GP method. PAH was calculated for both sexes using the Bayley-Pinneau (BP) method based on clinician- and BX-derived BA. PAH standard deviation scores (SDS) were compared with NFH-SDS and target height (TH)-SDS. Agreement was assessed using Bland-Altman analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpem-2026-0101_abs_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty patients (63.8\u202f%) were female. Mean ages at bone age assessment and NFH were 7.3 and 16.1 years, respectively. Mean prepubertal height-SDS was 0.0 in girls and\u00a0\u22120.25 in boys, while NFH-SDS was\u00a0\u22120.79 and\u00a0\u22121.14, respectively. Mean bone age according to clinician-GP was 7.80 years in girls and 8.16 in boys, and 7.69 and 8.14 years according to BX-GP. Clinician-based PAH-SDS was\u00a0\u22121.0 in girls and\u00a0\u22121.18 in boys, whereas BX-based PAH-SDS was\u00a0\u22120.86 and\u00a0\u22121.17, respectively. BX-based PAH was closer to NFH in girls (p&lt;0.001), with no significant difference in boys. In both sexes, PAH-SDS and NFH-SDS were significantly lower than TH-SDS (p&lt;0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_jpem-2026-0101_abs_004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PAH calculations using the BP method based on BX-derived GP bone age readings more accurately predicted NFH in patients with CAH.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1515\/jpem-2026-0101","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T01:55:54Z","timestamp":1777859754000},"page":"464-471","source":"Crossref","is-referenced-by-count":0,"title":["Automatic bone age assessment for adult height prediction in children with congenital adrenal hyperplasia"],"prefix":"10.1515","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9022-4010","authenticated-orcid":false,"given":"K\u00fcr\u015fat","family":"\u00c7etin","sequence":"first","affiliation":[{"name":"Department of Pediatric Endocrinology , Akdeniz University Hospital , Antalya , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1888-919X","authenticated-orcid":false,"given":"Ebru Barsal","family":"\u00c7etiner","sequence":"additional","affiliation":[{"name":"Department of Pediatric Endocrinology , Akdeniz University Hospital , Antalya , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9022-5294","authenticated-orcid":false,"given":"Yasemin Funda","family":"Bahar","sequence":"additional","affiliation":[{"name":"Department of Pediatric Endocrinology , Akdeniz University Hospital , Antalya , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9924-9775","authenticated-orcid":false,"given":"Ali","family":"T\u0131rtar","sequence":"additional","affiliation":[{"name":"Department of Pediatric Endocrinology , Akdeniz University Hospital , Antalya , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3550-1425","authenticated-orcid":false,"given":"Mesut","family":"Parlak","sequence":"additional","affiliation":[{"name":"Department of Pediatric Endocrinology , Akdeniz University Hospital , Antalya , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7637-9630","authenticated-orcid":false,"given":"Hale","family":"Tuhan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Endocrinology , Akdeniz University Hospital , Antalya , T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2026,5,5]]},"reference":[{"key":"2026060500564545759_j_jpem-2026-0101_ref_001","doi-asserted-by":"crossref","unstructured":"Martin, DD, Heil, K, Heckmann, C, Zierl, A, Schaefer, J, Ranke, MB, et al.. 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