{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:18:06Z","timestamp":1761743886567},"reference-count":0,"publisher":"Walter de Gruyter GmbH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>\n                  <jats:bold>Objective:<\/jats:bold> To determine levels of galectins (gal)-1 and -3 (implicated in angiogenesis\/immunologic mechanisms) in intrauterine growth restricted (IUGR), large (LGA) and appropriate for gestational age (AGA) pregnancies, as these groups differ in fat mass, angiogenic patterns and immune responses.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Methods:<\/jats:bold> Cord-blood (UC) gal-1 and -3 concentrations were measured in 30 IUGR, 30 LGA and 20 AGA singleton full-term infants and their mothers (MS).<\/jats:p>\n               <jats:p>\n                  <jats:bold>Results:<\/jats:bold> IUGR, LGA and AGA groups did not differ in gal-1 and -3 concentrations. UC gal-1 levels were lower when mothers were older [b=\u20130.651, CI 95% \u20131.186 (\u20130.116), P=0.018] and UC gal-3 levels were increased when mothers presented gestational diabetes [b=9.836, CI 95% 3.833- (15.839), P=0.002].<\/jats:p>\n               <jats:p>In IUGRs MS gal-3 and in LGAs UC gal-1 were decreased in multiparas [b=\u20135.372, CI 95% -9.584- (\u20131.161), P=0.014], and [b=\u20137.540, CI 95% -14.606- (\u20130.473), P=0.037], respectively.<\/jats:p>\n               <jats:p>No correlations were found between MS or UC gal-1 and gal-3 concentrations.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusions:<\/jats:bold> Lower UC gal-1 levels, when mothers were older, and increased UC gal-3 levels in cases of gestational diabetes, possibly reflect angiogenic activity. In multiparas, decreased MS gal-3 and UC gal-1 levels in IUGR\/LGA, respectively, might imply inflammatory response against immunosuppression expected in subsequent pregnancies, as compared to the first one.<\/jats:p>","DOI":"10.1515\/jpm-2013-0220","type":"journal-article","created":{"date-parts":[[2014,4,9]],"date-time":"2014-04-09T20:00:49Z","timestamp":1397073649000},"page":"305-309","source":"Crossref","is-referenced-by-count":10,"title":["Cord blood galectin-1 and -3 concentrations in term pregnancies with normal restricted and increased fetal growth"],"prefix":"10.1515","volume":"43","author":[{"given":"Theodora","family":"Boutsikou","sequence":"first","affiliation":[{"name":"Department of Neonatology, Athens University Medical School, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Giotaki","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Athens University Medical School, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Boutsikou","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Athens University Medical School, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Despina D.","family":"Briana","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Athens University Medical School, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stavroula","family":"Baka","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Athens University Medical School, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Despoina","family":"Piatopoulou","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical Biochemistry \u2013 Molecular Diagnostics, 2 nd Department of Pediatrics, Athens University Medical School, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demetrios","family":"Hassiakos","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Athens University Medical School, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demetrios","family":"Gourgiotis","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical Biochemistry \u2013 Molecular Diagnostics, 2 nd Department of Pediatrics, Athens University Medical School, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariadne","family":"Malamitsi-Puchner","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Athens University Medical School, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2014,4,9]]},"container-title":["Journal of Perinatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpm-2013-0220\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpm-2013-0220\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T03:22:29Z","timestamp":1678764149000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpm-2013-0220\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,9]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2014,4,9]]},"published-print":{"date-parts":[[2015,5,1]]}},"alternative-id":["10.1515\/jpm-2013-0220"],"URL":"https:\/\/doi.org\/10.1515\/jpm-2013-0220","relation":{},"ISSN":["1619-3997","0300-5577"],"issn-type":[{"value":"1619-3997","type":"electronic"},{"value":"0300-5577","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4,9]]}}}