{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T21:18:31Z","timestamp":1793395111964,"version":"4.5.0"},"reference-count":0,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>\n                  <jats:bold>Aim:<\/jats:bold> To analyze the role of maternal placental growth factor (PlGF) in the prediction of small for gestational age (SGA) birth weight in pregnancy complicated by type 1 diabetes mellitus (T1DM).<\/jats:p>\n               <jats:p>\n                  <jats:bold>Methods:<\/jats:bold> A prospective observational study on 59 normotensive T1DM pregnant women, assessing maternal PlGF concentrations between the 10<jats:sup>th<\/jats:sup>\u201314<jats:sup>th<\/jats:sup> and 22<jats:sup>nd<\/jats:sup>\u201325<jats:sup>th<\/jats:sup> weeks of gestation.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Results:<\/jats:bold> Number of SGA vs. non-SGA newborns was 11 (18.6%) vs. 48 (81.4%), respectively. First trimester PlGF serum concentrations (pg\/mL) were similar between SGA vs. non-SGA groups [data given as median (interquartile range)]: 65.5 (35.58\u2013159.20) vs. 68.23 (11.59\u2013150.03), respectively; P=0.44. A trend for lower PlGF concentrations was observed in the second trimester in the SGA vs. non-SGA group: 63.34 (12.79\u2013119.16) vs. 116.75 (33.93\u2013235.82); P=0.07. In the SGA group, PlGF concentrations did not differ between the first and the second trimester: 65.5 (35.58\u2013159.20) vs. 63.34 (12.79\u2013119.16), respectively; P=0.36. In the non-SGA group, PlGF concentrations were significantly higher at the gestational age of 22\u201325 weeks compared to 10\u201314 weeks [116.75 (33.93\u2013235.82) vs. 68.23 (11.59\u2013150.03); P=0.03).<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusions:<\/jats:bold> Decreased PlGF serum concentration in mid-pregnancy, as well as a lack of physiological increase in PlGF levels between early and mid-gestation, may precede development of SGA in women with T1DM.<\/jats:p>","DOI":"10.1515\/jpm-2013-0227","type":"journal-article","created":{"date-parts":[[2014,2,11]],"date-time":"2014-02-11T20:07:53Z","timestamp":1392149273000},"page":"629-633","source":"Crossref","is-referenced-by-count":15,"title":["Maternal serum placental growth factor and fetal SGA in pregnancy complicated by type 1 diabetes mellitus"],"prefix":"10.1515","volume":"42","author":[{"given":"Pawe\u0142","family":"Gutaj","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Women\u2019s Diseases, Poznan University of Medical Sciences, Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewa","family":"Wender-O\u017cegowska","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Women\u2019s Diseases, Poznan University of Medical Sciences, Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafa\u0142","family":"Iciek","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Women\u2019s Diseases, Poznan University of Medical Sciences, Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Zawiejska","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Women\u2019s Diseases, Poznan University of Medical Sciences, Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Pietryga","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Women\u2019s Diseases, Poznan University of Medical Sciences, Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacek","family":"Br\u0105zert","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Women\u2019s Diseases, Poznan University of Medical Sciences, Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2014,2,12]]},"container-title":["Journal of Perinatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpm-2013-0227\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpm-2013-0227\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T14:05:07Z","timestamp":1680357907000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpm-2013-0227\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,12]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2014,2,21]]},"published-print":{"date-parts":[[2014,9,1]]}},"alternative-id":["10.1515\/jpm-2013-0227"],"URL":"https:\/\/doi.org\/10.1515\/jpm-2013-0227","relation":{},"ISSN":["1619-3997","0300-5577"],"issn-type":[{"value":"1619-3997","type":"electronic"},{"value":"0300-5577","type":"print"}],"subject":[],"published":{"date-parts":[[2014,2,12]]}}}