{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T10:19:59Z","timestamp":1781086799531,"version":"3.54.1"},"reference-count":0,"publisher":"Walter de Gruyter GmbH","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>\n                  <jats:bold>Objective:<\/jats:bold> The PartoSure\u2122 time-to-delivery (TTD) test (AmniSure International, Boston, MA, USA) is a newly available bedside test for the prediction of time to spontaneous preterm delivery via the detection of placental alpha microglobulin-1. The objective of this study was to determine the efficacy of the test in predicting imminent delivery in 7 or 14 days from the time of testing.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Methods:<\/jats:bold> The study population consisted of 101 consecutively recruited pregnant women with singleton pregnancies between 20+0 and 36+6 weeks of gestation with symptoms of preterm labor, clinically intact amniotic membranes, and minimal cervical dilatation (\u22643 cm). The PartoSure\u2122 TTD test was performed on these patients and the test-to-spontaneous-delivery interval was calculated.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Results:<\/jats:bold> The PartoSure\u2122 TTD test predicted spontaneous preterm delivery within 7 days with 90.0% sensitivity, 93.8% specificity, 97.4% negative predictive value (NPV), and 78.3% positive predictive value (PPV). The test predicted spontaneous preterm delivery within 14 days with 80% sensitivity, 96.1% specificity, 93.6% NPV, and 87.0% PPV.<\/jats:p>\n               <jats:p>\n                  <jats:bold>Conclusion:<\/jats:bold> A positive PartoSure\u2122 TTD test in patients presenting with symptoms of preterm labor, intact membranes, and minimal cervical dilatation (\u22643 cm) indicated spontaneous preterm delivery will occur within 7 days with a high degree of accuracy. A negative result indicated that spontaneous preterm delivery within 14 days is highly unlikely.<\/jats:p>","DOI":"10.1515\/jpm-2013-0234","type":"journal-article","created":{"date-parts":[[2013,12,12]],"date-time":"2013-12-12T20:13:47Z","timestamp":1386879227000},"page":"473-477","source":"Crossref","is-referenced-by-count":37,"title":["Evaluation of a novel placental alpha microglobulin-1 (PAMG-1) test to predict spontaneous preterm delivery"],"prefix":"10.1515","volume":"42","author":[{"given":"Tanja","family":"Nikolova","sequence":"first","affiliation":[{"name":"University Clinic of Obstetrics and Gynecology, Skopje, Republic of Macedonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oleg","family":"Bayev","sequence":"additional","affiliation":[{"name":"Research Center of Obstetrics, Gynecology and Perinatology of the Ministry of Healthcare and Social Development of the Russian Federation, Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha","family":"Nikolova","sequence":"additional","affiliation":[{"name":"University Clinic of Obstetrics and Gynecology, Skopje, Republic of Macedonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Carlo","family":"Di Renzo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Perugia, Perugia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2013,12,13]]},"container-title":["Journal of Perinatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpm-2013-0234\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpm-2013-0234\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T03:26:19Z","timestamp":1678764379000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyter.com\/document\/doi\/10.1515\/jpm-2013-0234\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,13]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2014,1,11]]},"published-print":{"date-parts":[[2014,7,1]]}},"alternative-id":["10.1515\/jpm-2013-0234"],"URL":"https:\/\/doi.org\/10.1515\/jpm-2013-0234","relation":{},"ISSN":["1619-3997","0300-5577"],"issn-type":[{"value":"1619-3997","type":"electronic"},{"value":"0300-5577","type":"print"}],"subject":[],"published":{"date-parts":[[2013,12,13]]}}}