{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T00:30:35Z","timestamp":1783211435217,"version":"3.54.6"},"reference-count":20,"publisher":"Walter de Gruyter GmbH","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>This article looks at the association of maternal blood pressure with the blood pressure of the offspring from birth to childhood. The Barker hypothesis states that maternal and \u201c<jats:italic>in utero<\/jats:italic>\u201d attributes during pregnancy affect a child\u2019s cardiovascular health throughout life. We present an analysis of a unique dataset that consists of three distinct developmental processes: maternal cardiovascular health during pregnancy; fetal development; and child\u2019s cardiovascular health from birth to 14 years. This study explored whether a mother\u2019s blood pressure reading in pregnancy predicts fetal development and determines if this in turn is related to the future cardiovascular health of the child. This article uses data that have been collected prospectively from a Jamaican cohort which involves the following three developmental processes: (1) maternal cardiovascular health during pregnancy which is the blood pressure and anthropometric measurements at seven time-points on the mother during pregnancy; (2) fetal development which consists of ultrasound measurements of the fetus taken at six time-points during pregnancy; and (3) child\u2019s cardiovascular health which consists of the child\u2019s blood pressure measurements at 24 time-points from birth to 14 years. The inter-relationship of these three processes was examined using linear mixed effects models. Our analyses indicated that attributes later in childhood development, such as child\u2019s weight, child\u2019s baseline systolic blood pressure (SBP), age and sex, predict the future cardiovascular health of children. The results also indicated that maternal attributes in pregnancy, such as mother\u2019s baseline SBP and SBP change, predicted significantly child\u2019s SBP over time.<\/jats:p>","DOI":"10.1515\/jpm-2014-0038","type":"journal-article","created":{"date-parts":[[2014,8,28]],"date-time":"2014-08-28T10:02:07Z","timestamp":1409220127000},"page":"695-701","source":"Crossref","is-referenced-by-count":3,"title":["Association of maternal blood pressure in pregnancy with blood pressure of their offspring through adolescence"],"prefix":"10.1515","volume":"43","author":[{"given":"Tamika","family":"Royal-Thomas","sequence":"first","affiliation":[{"name":"Tropical Medicine Research Institute, University of the West Indies, Mona Campus, Kingston 7, Jamaica"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"McGee","sequence":"additional","affiliation":[{"name":"Statistics Department, Florida State University, Tallahassee, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debajyoti","family":"Sinha","sequence":"additional","affiliation":[{"name":"Statistics Department, Florida State University, Tallahassee, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clive","family":"Osmond","sequence":"additional","affiliation":[{"name":"MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terrence","family":"Forrester","sequence":"additional","affiliation":[{"name":"UWI Solutions for Developing Countries, University of the West Indies, Mona Campus, Kingston 7, Jamaica"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2014,8,28]]},"reference":[{"key":"2023031403222333357_j_jpm-2014-0038_ref_001_w2aab2b8c19b1b7b1ab2ab1Aa","doi-asserted-by":"crossref","unstructured":"Barker D. 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