{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T09:46:46Z","timestamp":1648720006135},"reference-count":34,"publisher":"Walter de Gruyter GmbH","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Inhaled nitric oxide (iNO) is a well-established treatment for neonatal hypoxic respiratory failure (HRF). However, iNO therapy initiation criteria have not been standardized. This report describes a follow-up survey administered to neonatologists who had completed an Awareness, Trial, and Usage Survey. The objectives were to compare stated target oxygenation index (OI) versus actual OI at which iNO is initiated in respondents\u2019 patients and identify factors associated with iNO initiation at other levels.<\/jats:p><jats:p>Neonatologists provided iNO-treated HRF patient data. Target and actual OI at initiation were determined. Patient groups were stratified by actual OI deviation from target [&lt;4; at (\u00b13); above: 4\u201310, 11\u201320, &gt;20; not measured]. Reasons for above-target OI were determined.<\/jats:p><jats:p>Of 83 invited neonatologists, 26 (31%) participated, providing data for 128 patients; 85\/128 patients (66%) had OI measured at initiation with neonatologist-stated mean target OI 18.8\u00b15.8. Actual mean OI was 26.2\u00b110.3. iNO was initiated \u2264 target in 30\/85 patients (35%); most [55\/85 (65%)] had iNO initiated when OI was above target. Patients aged \u22641 day and those receiving a fraction of inspired oxygen (FiO<\/jats:p><jats:p>Among surveyed neonatologists who treat infants with HRF with pulmonary hypertension (PH), there is a disparity between stated target versus actual OI for iNO initiation, particularly among infants &lt;1 day old and those receiving FiO<\/jats:p>","DOI":"10.1515\/jpm-2014-0242","type":"journal-article","created":{"date-parts":[[2014,9,4]],"date-time":"2014-09-04T17:53:39Z","timestamp":1409853219000},"source":"Crossref","is-referenced-by-count":0,"title":["Target versus actual oxygenation index at initiation of inhaled nitric oxide in neonates with hypoxic respiratory failure: survey results from 128 patient cases"],"prefix":"10.1515","volume":"42","author":[{"given":"Sergio","family":"Golombek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise","family":"Suttner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reuben","family":"Ehrlich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim","family":"Potenziano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref311","first-page":"336","article-title":"Neonatal Inhaled Nitric Oxide Study Group Inhaled nitric oxide in full - 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