{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T06:54:19Z","timestamp":1751525659961},"reference-count":30,"publisher":"Walter de Gruyter GmbH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Higher 1<\/jats:p><jats:p>To compare IP-10 and ITAC levels in neonatal cord blood from gestations complicated by severe preeclampsia vs. gestational age-matched controls.<\/jats:p><jats:p>Umbilical cord vessels were sampled following delivery of women with severe preeclampsia (n=30) \u226536 weeks to measure plasma IP-10 and ITAC levels and compared to corresponding controls matched for parity as well as maternal and gestational age. Chemokines were measured by specific ELISAs and expressed as pg\/mL. Rho Spearman\u2019s coefficients were calculated to establish correlations between chemokine values and various numeric variables.<\/jats:p><jats:p>Preeclamptic cases displayed significantly lower median plasma umbilical artery and vein levels of both chemokines when compared to controls (IP-10: 23.4 vs. 31.4 and 2.0 vs. 24.6 pg\/mL, P&lt;0.05; and ITAC: 2.0 vs. 13.9 and 11.9 vs. 31.6 pg\/mL, P&lt;0.05, in artery and vein, respectively). There was a significant correlation between levels of both chemokines (r<\/jats:p><jats:p>In contrast to elevated 1<\/jats:p>","DOI":"10.1515\/jpm-2014-0371","type":"journal-article","created":{"date-parts":[[2015,3,4]],"date-time":"2015-03-04T17:10:56Z","timestamp":1425489056000},"source":"Crossref","is-referenced-by-count":7,"title":["Umbilical cord plasma interferon-induced protein 10 (IP-10) and interferon-induced T-cell alpha chemoattractant (ITAC) levels are lower in women with severe preeclampsia"],"prefix":"10.1515","volume":"44","author":[{"given":"Peter","family":"Chedraui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilio J.","family":"Sol\u00eds","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faustino R.","family":"P\u00e9rez-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred","family":"Schatz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umit","family":"Kayisli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo S.","family":"Escobar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita","family":"Loja-Chango","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Hidalgo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles J.","family":"Lockwood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref171","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.bpobgyn.2010.10.009","article-title":"Deep placentation","volume":"25","year":"2011","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"ref251","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.ijgo.2004.09.024","article-title":"Factors associated with inadequate prenatal care in Ecuadorian women","volume":"88","year":"2005","journal-title":"Int J Gynaecol Obstet"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.bpobgyn.2010.10.009","article-title":"Deep placentation","volume":"25","year":"2011","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"ref241","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1471-2172-11-59","article-title":"Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array","volume":"11","year":"2010","journal-title":"BMC Immunol"},{"key":"ref181","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1172\/JCI119387","article-title":"Human cytotrophoblasts adopt a vascular phenotype as they differentiate. 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