{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T22:47:56Z","timestamp":1773096476347,"version":"3.50.1"},"reference-count":106,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To compare the frequency of histologic chorioamnionitis and funisitis among women experiencing preterm labor, preterm premature rupture of membranes (PROM) and cervical insufficiency.<\/jats:p><jats:p>This retrospective cohort study included singleton pregnant women who delivered at \u226436 weeks of gestation. The patients with preterm birth were subdivided into preterm labor (n=117), preterm PROM (n=153), and cervical insufficiency (n=20). All placentas were examined for pathology, according to the criteria of<\/jats:p><jats:p>1) Histologic chorioamnionitis was diagnosed in 48.7% (57\/117) of cases with preterm labor, 47.4% (73\/153) with preterm PROM, and 75.0% (15\/20) with cervical insufficiency. Funisitis was detected in 11.1% (13\/117) of cases with preterm labor, 15.7% (24\/153) with preterm PROM, and 40.0% (8\/20) with cervical insufficiency. 2) Frequency of histologic chorioamnionitis was higher in cases with cervical insufficiency compared to preterm PROM. Frequency of funisitis was higher in cases with cervical insufficiency compared to both preterm labor and preterm PROM (P&lt;0.05). The difference in frequency of funisitis remained significant after adjustment for gestational age at delivery and cervical dilatation at diagnosis. 3) Frequency of grade 2 funisitis was higher in cases with cervical insufficiency (35.0%, 7\/20) compared to both preterm labor (6.8%, 8\/117) and preterm PROM (9.8%, 15\/153) (P=0.001). And the difference remained significant after adjustment for gestational age at delivery and cervical dilatation at diagnosis.<\/jats:p><jats:p>: The highest frequency of funisitis was observed in cervical insufficiency among cases with spontaneous preterm birth.<\/jats:p>","DOI":"10.1515\/jpm-2015-0123","type":"journal-article","created":{"date-parts":[[2016,1,22]],"date-time":"2016-01-22T09:48:33Z","timestamp":1453456113000},"source":"Crossref","is-referenced-by-count":11,"title":["Funisitis is more common in cervical insufficiency than in preterm labor and preterm premature rupture of membranes"],"prefix":"10.1515","volume":"44","author":[{"given":"Joohee","family":"Choi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong Woo","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Byoung Jae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ye-Jin","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Hee","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung Mi","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"ref421","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1196\/annals.1389.032","article-title":"Physiology of upward transport in the human female genital tract","volume":"1101","year":"2007","journal-title":"Ann N Y Acad Sci."},{"key":"ref741","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/infdis\/145.1.1","article-title":"Quantitative bacteriology of amniotic fluid from women with clinical intraamniotic infection at 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