{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T10:37:17Z","timestamp":1721299037117},"reference-count":20,"publisher":"Walter de Gruyter GmbH","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec id=\"j_jpm-2015-0361_s_999_w2aab2b8c27b1b7b1aab1c15b1Aa\">\n                  <jats:title>Aim:<\/jats:title>\n                  <jats:p> To evaluate the short-term effects of blood transfusion on iron status [hemoglobin, ferritin, soluble transferrin receptor (sTfR), and reticulocyte count], hepcidin, and erythropoietin in stable preterm infants.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2015-0361_s_998_w2aab2b8c27b1b7b1aab1c15b2Aa\">\n                  <jats:title>Method:<\/jats:title>\n                  <jats:p> Sixty-three preterm infants treated with red blood cell transfusions (RBCTs) were included. Venous blood samples were collected before and within 24 h after each transfusion.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2015-0361_s_997_w2aab2b8c27b1b7b1aab1c15b3Aa\">\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p> Hemoglobin concentration increased after RBCT (7.2\u00b11.2 g\/dL vs. 13.7\u00b12.3 g\/dL, P=0.02), as well as ferritin [131 (63\u2013110.4) ng\/mL vs. 211 (125.7\u2013299.2) ng\/mL, P=0.05); reticulocyte count decreased. sTfR did not change. Hepcidin serum levels increased from 37.5 (21.3\u201384.7) ng\/mL to 72.6 (31.3\u2013126.2) ng\/mL, (P=0.04) and erythropoietin decreased (48\u00b119 pg\/mL vs. 29\u00b117 pg\/mL, P=0.06) after RBCT. A positive linear correlation was found (R<jats:sup>2<\/jats:sup>=0.76, P=0.0001) between hepcidin and ferritin levels of post-minus-pre RBCT. Hepcidin levels increased significantly in preterm infants who received RBCT after 1 month of age compared to those who received RBCT at &lt;1 month (P=0.03). No correlation was found between gestational age, weight appropriate for age, or length of blood storage and hepcidin levels.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec id=\"j_jpm-2015-0361_s_996_w2aab2b8c27b1b7b1aab1c15b4Aa\">\n                  <jats:title>Conclusion:<\/jats:title>\n                  <jats:p> Preterm infants can control iron levels by regulating hepcidin and decreasing erythropoietin. This ability varies with postnatal age.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1515\/jpm-2015-0361","type":"journal-article","created":{"date-parts":[[2016,3,18]],"date-time":"2016-03-18T23:03:51Z","timestamp":1458342231000},"page":"919-923","source":"Crossref","is-referenced-by-count":9,"title":["Iron homeostasis after blood transfusion in stable preterm infants \u2013 an observational study"],"prefix":"10.1515","volume":"44","author":[{"given":"Jacky","family":"Herzlich","sequence":"first","affiliation":[{"name":"Department of Neonatology, Meir Medical Center, Kfar Saba, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ita","family":"Litmanovitz","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Meir Medical Center, Kfar Saba, Israel"},{"name":"Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rivka","family":"Regev","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Meir Medical Center, Kfar Saba, Israel"},{"name":"Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofia","family":"Bauer","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Meir Medical Center, Kfar Saba, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gisela","family":"Sirota","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Meir Medical Center, Kfar Saba, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zvi","family":"Steiner","sequence":"additional","affiliation":[{"name":"Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel"},{"name":"Department of Pediatric Surgery, Meir Medical Center, Kfar Saba, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shmuel","family":"Arnon","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Meir Medical Center, Kfar Saba, Israel"},{"name":"Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2016,3,18]]},"reference":[{"key":"2023033121172598808_j_jpm-2015-0361_ref_001_w2aab2b8c27b1b7b1ab2b1b1Aa","doi-asserted-by":"crossref","unstructured":"Shafir T, Angulo-Barroso R, Jing Y, Angelilli ML, Jacobson SW, Lozoff B. 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